Results 101 to 110 of about 563,218 (303)

Nurse staffing levels revisited: a consideration of key issues in nurse staffing levels and skill mix research. [PDF]

, 2009
AIM: This paper revisits the published evidence relating to how nurse staffing levels impact on patient, nurse and service outcomes and considers the implications of this body of research for nurse managers in their quest to determine optimum nursing ...
Aiken, Aiken, Al-Kandari, Arthur, Audit Commission, Buchan, Budge, Chaguturu, Chalmers, Chang, Currie, Department of Health, Department of Health, Department of Health, Donaldson, Edwards, Estabrooks, Garrett, Gerdtz, Greenhalgh, Griffiths, Hegney, House of Commons Public Accounts Committee, Hurst, Hurst, Hurst, Kane, Kirkpatrick, Konetzka, Kovner, Lang, Lankshear, Maben, Mannion, McKeown, Morgan, Moyle, Naish, Needleman, Page, Pearson, Rafferty, Robinson, Sasichay-Akkadechanunt, Scott, Scott, Sheward, Sochalski, Stone, Tervo-Heikkinen, Thungjaroenkul, Torangeau, Torangeau, Torangeau, Unruh, Upenieks   +55 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Developing sustainable service user involvement practices in mental health services in Sweden: the "Userinvolve" research program protocol. [PDF]

Front Psychiatry, 2023
Markström U, Näslund H, Schön UK, Rosenberg D, Bejerholm U, Gustavsson A, Jansson M, Argentzell E, Grim K, Engdahl P, Nouf F, Lilliehorn S, Svedberg P.   +12 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

SERVICE USER INVOLVEMENT IN SOCIAL WORK PRACTICE, EDUCATION AND RESEARCH IN BOSNIA-HERZEGOVINA

Ljetopis socijalnog rada, 2009
Despite the fact that the social work profession is considered to be a profession “promoting ... empowerment and liberation of individuals in order to attain greater level of well-being“, the inclusion of the user perspective is a relatively new and ...
Sanela Čekić Bašić
doaj  

Private Sector Involvement in Urban Solid Waste Collection. Performance, capacity and regulations in five cities in Ghana [PDF]

, 2011
This thesis focuses on the private sector involvement in solid waste collection, and the influence of private sector capacity and local governments‘ regulations on private sector performance.
Oduro-Kwarteng, S. (Sampson)
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

A Rapid Review of the Factors That Influence Service User Involvement in Interprofessional Education, Practice, and Research. [PDF]

Int J Environ Res Public Health, 2022
Sy MP, Panotes A, Cho D, Pineda RC, Martin P.   +4 more
europepmc   +1 more source

Satellite-based delivery of educational content to geographically isolated communities: A service based approach [PDF]

, 2007
Enabling learning for members of geographically isolated communities presents benefits in terms of promoting regional development and cost savings for governments and companies.
B Hall, BW Tuckerman, G Blakowski, Gheorghita Ghinea, HM Selm, Lampros Stergioulas, M Gotschall, M Weller, P Henry, S Sanz, Sherry Y. Chen, Sofia Tsekeridou, Tacha Serif, Thanassis Tiropanis   +13 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source