Results 201 to 210 of about 4,166 (249)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Experimental Investigation of the Flexural Performance of Continuous Self-Compacting Concrete Beams with Natural and Recycled Aggregates. [PDF]

Materials (Basel)
Petrović Ž, Milošević B, Spasojević Šurdilović M, Zorić A, Turnić D.   +4 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Reinforced Fill Structure with Alternative Fill Materials: An Application of Geogrid Creep Strain Analysis Using Numerical Modeling. [PDF]

Materials (Basel)
Khan AR, Di Emidio G.
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Enhancing translational medical research through proof-of-concept services: clinicians' perspectives. [PDF]

Sci Rep
Yuan L, Zhao P, Zhang J, Xu X, Jin M, Fang Z, Wang C, Li M.   +7 more
europepmc   +1 more source

Effects of Displacement Piles for Dike Reinforcement on Adjacent Buildings. [PDF]

Geotech Geol Eng (Dordr)
Ahmad M, Brinkgreve RBJ, Jonkman SN.
europepmc   +1 more source

Evaluation of Pearlite Steel Thermite Weldments' Hydrogen Degradation for Application of Additively Manufactured Crack-Resistant Material Inserts. [PDF]

Materials (Basel)
Kawiak M, Balitskii AI, Królikowski MA, Balitska VO, Dowejko JM.   +4 more
europepmc   +1 more source

Analysis of functional and serviceability performance in sustainable yarns and socks by using multi-response optimization technique. [PDF]

Sci Rep
Jamshaid H, Chandan V, Ahmad A, Mishra RK, Muller M.   +4 more
europepmc   +1 more source

Study on the grouting repair performance of shield tunnel segments based on high-fluidity slurry. [PDF]

Sci Rep
Huang K, Zhou K, Huang B, Wu X, Li Z, Xing K.   +5 more
europepmc   +1 more source