Results 61 to 70 of about 4,166 (249)

Service Model for the Service Configuration [PDF]

open access: yes, 2013
Service is a concept difficult to define. It has been extensively used in different contexts. According with literature a service can be seeing: as an activity or as an output of a process.By service customization we mean the definition and adaptation of a service according to the customer’ requirements, when this customization process is carried out ...
Jose Angel Lakunza   +2 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Sensing and Monitoring for Stadium Structures: A Review of Recent Advances and a Forward Look

open access: yesFrontiers in Built Environment, 2017
Stadiums like those used for sporting or concert events are distinct from other civil engineering structures due to several different characteristics. Some challenges mainly originate from the interaction with the human factor, as stadiums are subjected ...
Fikret Necati Catbas   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

TEMPERATURE DISTRIBUTION IN MULTILAYER METAL-CERAMIC COATINGS UNDER NONSTATIONARY THERMAL EFFECTS

open access: yesНаучный вестник МГТУ ГА, 2017
Progress in the aircraft engine construction is determined by the increase of operation parameters of gas turbine engines, which is inevitably accompanied by an increase of operating temperatures and load for the vital elements of the turbine hot ducts ...
V. M. Samoilenko   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Accessibility and Serviceability Assessment to Inform Offshore Wind Energy Development and Operations off the US East Coast

open access: yesWind Energy
The economic success of offshore wind energy projects relies on accurate projections of the construction and operations and maintenance (O&M) costs. These projections must consider the logistical complexities introduced by adverse met‐ocean conditions ...
Cory Petersen   +7 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy