Results 141 to 150 of about 1,934,582 (298)

Land Reforms in Cuba: First Empirical Assessment on Productivity Using Crop‐Level Panel Data

open access: yesEconomics of Transition and Institutional Change, EarlyView.
ABSTRACT Land reforms implemented in Cuba since 2008 have aimed to increase agricultural production by distributing state‐owned idle lands with land‐use rights. The reforms restricted farmers with the rights from cultivating perennial and capital‐intensive crops.
Yoshihiko Hashiguchi   +1 more
wiley   +1 more source

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

open access: yesThe FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero   +8 more
wiley   +1 more source

Servicios bibliotecarios

open access: yes, 2006
El presente volumen está integrado por nueve contribuciones sobre temas que, dentro del área académica de Servicios Bibliotecarios, son relevantes para la formación de los futuros bibliotecólogos que se desempeñen en el ámbito de los servicios bibliotecarios que brindan las unidades de información para atender los requerimientos informativos de sus ...
Figueroa Alcántara, Hugo Alberto   +1 more
openaire   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

open access: yesThe FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti   +3 more
wiley   +1 more source

Assessing soil and native high Andean grassland quality under grazing: A case study from the wet Puna of Peru

open access: yesGrassland Science, EarlyView.
Abstract High Andean grasslands are vulnerable to changes in their nutritional quality and carbon sequestration capacity, especially in grazing systems. This study evaluated soil quality and native grasses by measuring carbon, physicochemical parameters, and the nutritional quality of predominant species in the wet Puna of Junín, Peru.
Alberto Arias‐Arredondo   +5 more
wiley   +1 more source

Imaging Point Source Groundwater Discharges in a Confined Coastal Aquifer Using Electrical Resistivity

open access: yesGroundwater, EarlyView.
Marine electrical resistivity tomography (ERT) is applied to characterize point‐source submarine groundwater discharge (PSGD) along NW Yucatán. ERT observations and forward modeling constrain conduit detectability under varying hydrogeological conditions.
Mariana Gómez‐Nicolás   +6 more
wiley   +1 more source

Evaluation of the effectiveness and safety of anti‐CGRP monoclonal antibodies in patients with migraine and autoimmune diseases: IMMUNO‐CGRP study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to evaluate demographic characteristics, treatment effectiveness, and safety outcomes in patients with migraine undergoing anti‐calcitonin gene‐related peptide (CGRP) treatments regarding the presence of autoimmune diseases. Background CGRP has an important role in migraine pathophysiology through neuronal modulation
María Clara García‐Castillo   +37 more
wiley   +1 more source

Delphi consensus: First‐line use of biologics and small molecules in hidradenitis suppurativa

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This Delphi Consensus study identified upgrade criteria for the use of biologics and small molecules as first‐line therapy in hidradenitis suppurativa (HS). European HS experts evaluated 16 clinical scenarios, voting on eligibility for therapy escalation.
Georgios Nikolakis   +54 more
wiley   +1 more source

Treatment‐associated phenotype switching between psoriasis and atopic dermatitis

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This international, multicentre real‐world study of 148 patients’ documents treatment‐associated, bidirectional phenotype switching between psoriasis and atopic dermatitis. Psoriasis‐to‐eczematous switches occurred predominantly with IL‐17 and IL‐23 inhibitors, whereas AD‐to‐psoriasiform switches occurred exclusively during treatment with biologic ...
Tiago Torres   +28 more
wiley   +1 more source

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