Results 111 to 120 of about 45,683 (253)

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

The composition of the essential oil of Artemisia annua L. growing wild in Iran

Journal of Medicinal Plants, 2002
The composition of essential oil of the leaves of Artemisia annua L. growing wild in Iran, were determined by the use of GC/MS. The leaf essential oils obtained by hydrodistilation.
Hossein Lari yazdi, Ramezanali Khavarinejad, Abdolhossein Roustaian   +2 more
doaj  

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

Bolinaquinone: A novel cytotoxic sesquiterpene hydroxyquinone from a Philippine Dysidea sponge

, 1998
Sesquiterpene hydroxyquinones and hydroquinones have been isolated from various sponges.3-16 The sesquiterpene moiety of these metabolites usually have the normal drimane skeleton, as exemplified by spongiaquinone (1),3 a rearranged drimane skeleton, as ...
De Guzman, FS, Barrows, LR, Ireland, CM, Concepcion, GP, Mangalindan, GC, Mayne, CL, Copp, BR   +6 more
core   +1 more source

Synthesis of Novel Nitro-Halogenated Aryl-Himachalene Sesquiterpenes from Atlas Cedar Oil Components: Characterization, DFT Studies, and Molecular Docking Analysis against Various Isolated Smooth Muscles

Molecules
We report the synthesis of two novel halogenated nitro-arylhimachalene derivatives: 2-bromo-3,5,5,9-tetramethyl-1-nitro-6,7,8,9-tetrahydro-5H-benzo[7]annulene (bromo-nitro-arylhimachalene) and 2-chloro-3,5,5,9-tetramethyl-1,4-dinitro-6,7,8,9-tetrahydro ...
Youssef Edder, Issam Louchachha, Abdelmajid Faris, Mohamed Maatallah, Khalil Azzaoui, Mohammed Zerrouk, Mohamed Saadi, Lahcen El Ammari, Moha Berraho, Mohammed Merzouki, Brahim Boualy, Belkheir Hammouti, Rachid Sabbahi, Abdallah Karim, Mohammed M. Alanazi, Alicia Ayerdi Gotor, Larbi Rhazi   +16 more
doaj   +1 more source

Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy

Phytotherapy Research, EarlyView.
This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi, LuLu Zhang, Lan Yan, Qi Geng, Li Li, Xiaojuan He, Ning Zhao, Yong Tan, Xiaomeng Zhang, Cheng Lu   +9 more
wiley   +1 more source

A new marasmane sesquiterpene from the Basidiomycete Russula foetens. Z Naturforsch

, 2020
A new marasmane sesquiterpene, named lactapiperanol E (1), was isolated from the fruiting bodies of Russula foetens together with a known sesquiterpene lactapiperanol A (2).
Ren-Xiang Tan, Fei Wang, Jian-Chang Du, Hui-Ming Ge, Ji-Kai Liu, Xing-Na Wang   +5 more
core  

A new sesquiterpene from the South China Sea gorgonian coral Subergorgia suberosa

, 2016
A new sesquiterpene, namely suberosoid (1), was isolated from the South China Sea gorgonian coral Subergorgia suberosa. The chemical structure of 1 was established as an unusual sesquiterpene containing 4-methylenecyclohex-2-enone system, by extensive ...
Yuan-Tao Hao (2810245), Mu-Wu Xu (2810242)   +1 more
core   +1 more source