Results 31 to 40 of about 70,303 (204)
Set-Valued Analysis, Viability Theory and Partial Differential Inclusions [PDF]
Systems of first-order partial differential inclusions -- solutions of which are feedbacks governing viable trajectories of control systems -- are derived.
Aubin, J.-P., Frankowska, H.
core
Characterization of the monotone polar of subdifferentials
We show that a point is solution of the Minty variational inequality of subdifferential type for a given function if and only if the function is increasing along rays starting from that point.
Lassonde, Marc
core +3 more sources
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The main purpose of this paper is to introduce and study a new class of generalized nonlinear set-valued quasi-variational inclusions system involving -accretive mappings in Banach spaces. By using the resolvent operator due to Lan-Cho-Verma associated
Jin MaoMing, Li Hong-Gang, Xu AnJian
doaj
We prove an existence result for a p-Laplacian problem set in the whole Euclidean space and exhibiting a critical term perturbed by a singular, convective reaction.
Baldelli Laura, Guarnotta Umberto
doaj +1 more source
Results on Solution Set in Certain Interval-Valued Controlled Models
In this paper, a class of controlled variational control models is studied by considering the notion of (q,w)−π-invexity. Our aim is to investigate a solution set in the considered interval-valued controlled models.
Savin Treanţă, Omar Mutab Alsalami
doaj +1 more source
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source

