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MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Workflow for Statistical Analysis of Environmental Mixtures. [PDF]

Environ Health Perspect
Joubert BR, Palmer G, Dunson D, Kioumourtzoglou MA, Coull BA.   +4 more
europepmc   +1 more source

REMOTE-Neuro: co-produced recommendations to optimise remote neurology. [PDF]

BMJ Neurol Open
Fuller P, Fearn S, Dace S, Wollam A, Zarkali A, Cowan A, Mountney S, Carr G, Eriksson SH, Kipps C.   +9 more
europepmc   +1 more source

Singularity in nonlinear systems: differential inclusion model for the standard and transformed fractional pantograph equation. [PDF]

Sci Rep
Mobayen S, Ghaderi M, Shabibi M, Parvaneh Masiha H, Rezapour S.   +4 more
europepmc   +1 more source

Extended Divergence-Measure Fields, the Gauss-Green Formula and Cauchy Fluxes. [PDF]

Arch Ration Mech Anal
Chen GG, Irving C, Torres M.
europepmc   +1 more source

A Modified Complex-Valued Encoding Greater Cane Rat Algorithm for Global Optimization and Constrained Engineering Applications. [PDF]

Biomimetics (Basel)
Xu Y, Wu Y, Zhang J.
europepmc   +1 more source

Adaptive low-light image enhancement using Interval-Valued Intuitionistic Fuzzy Set optimized by Reptile Search Algorithm. [PDF]

Front Artif Intell
Yogambaram H, Sivabalakrishnan M, Balaji S.   +2 more
europepmc   +1 more source

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Jensen's inequalities for set-valued and fuzzy set-valued functions

Fuzzy Sets and Systems, 2021
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Deli Zhang, Caimei Guo, Degang Chen 0002, Guijun Wang   +3 more
openaire   +1 more source