Results 61 to 70 of about 1,160,362 (285)

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman   +17 more
wiley   +1 more source

Ekeland's Variational Principle for Set-Valued Functions [PDF]

open access: yesSIAM Journal on Optimization, 2011
The authors extend Ekeland's variational principle to the case of set-valued mappings by using a set of directions and some particular partial orders related to it. Then, as an application they establish some sufficient conditions for the existence of an error bound of a finite system of inequalities of lower semicontinuous functions on a Banach space.
Liu, C. G., Ng, K. F.
openaire   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy   +5 more
wiley   +1 more source

Novel Parameterized Score Functions on Interval-Valued Intuitionistic Fuzzy Sets With Three Fuzziness Measure Indexes and Their Application

open access: yesIEEE Access, 2019
To explore the essential law of fuzziness of interval-valued intuitionistic fuzzy sets (IVIFSs), the entropy brought by interval values is studied.
Fangwei Zhang   +4 more
doaj   +1 more source

Hesitant Bipolar-Valued Fuzzy Soft Sets and Their Application in Decision Making

open access: yesComplexity, 2020
As an extension of fuzzy sets, hesitant bipolar-valued fuzzy set is a new mathematical tool for dealing with fuzzy problems, but it still has the problem with the inadequacy of the parametric tools.
Jin-Ying Wang, Yan-Ping Wang, Lei Liu
doaj   +1 more source

Molecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk   +9 more
wiley   +1 more source

Hybrid Binary Logarithm Similarity Measure for MAGDM Problems under SVNS Assessments [PDF]

open access: yesNeutrosophic Sets and Systems, 2018
Single valued neutrosophic set is an important mathematical tool for tackling uncertainty in scientific and engineering problems because it can handle situation involving indeterminacy.
Kalyan Mondal   +2 more
doaj   +1 more source

The complexity of finite-valued CSPs

open access: yes, 2016
We study the computational complexity of exact minimisation of rational-valued discrete functions. Let $\Gamma$ be a set of rational-valued functions on a fixed finite domain; such a set is called a finite-valued constraint language.
Thapper, Johan, Zivny, Stanislav
core   +1 more source

Criterion‐Related Validity of the Neuropsychological Quick Assessment for Screening Cognitive, Motor, and Behavioral Impairments in Patients With Pediatric Brain Tumors: An Observational Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neuropsychological complications may impair the qualitative prognosis of patients with pediatric brain tumors. However, multifaceted evaluations cannot be conducted in all patients because they are time consuming and burdensome for patients.
Ami Tabata   +9 more
wiley   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson   +20 more
wiley   +1 more source

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