Results 61 to 70 of about 1,162,739 (282)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Berge's Theorem for Noncompact Image Sets

open access: yes, 2012
For an upper semi-continuous set-valued mapping from one topological space to another and for a lower semi-continuous function defined on the product of these spaces, Berge's theorem states lower semi-continuity of the minimum of this function taken over
Feinberg, Eugene A.   +2 more
core   +3 more sources

Subtraction and Division Operations of Simplified Neutrosophic Sets

open access: yesInformation, 2017
A simplified neutrosophic set is characterized by a truth-membership function, an indeterminacy-membership function, and a falsity-membership function, which is a subclass of the neutrosophic set and contains the concepts of an interval neutrosophic set ...
Jun Ye
doaj   +1 more source

Balanced ternary addition using a gated silicon nanowire

open access: yes, 2011
We demonstrate the proof of principle for a ternary adder using silicon metal-on-insulator single electron transistors (SET). Gate dependent rectifying behavior of a single electron transistor results in a robust three-valued output as a function of the ...
Klein, M.   +5 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Traditional continuum theory arising in inverse limits with set-valued functions

open access: yesRevista Integración, 2019
In the years since their introduction in 2004, almost 100 articles and books have been written on the subject of inverse limits with set-valued functions.
W. T. Ingram
doaj  

Modular decomposition of the NOR-TSUM multiple-valued PLA [PDF]

open access: yes, 1997
A method for designing PLA-based combinational circuits by modular decomposition is presented. Main subjects are 1) Specific properties of TSUM operator, 2) MIN-TSUM and NOR-TSUM expansions with respect to the bound set, X1 of variables, 3) Realization ...
Holowinski, G   +2 more
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Interval-Valued Pythagorean Hesitant Fuzzy Set and Its Application to Multiattribute Group Decision-Making

open access: yesComplexity, 2020
Pythagorean hesitant fuzzy sets are widely watched because of their excellent ability to deal with uncertainty, imprecise and vague information. This paper extends Pythagorean hesitant fuzzy environments to interval-valued Pythagorean hesitant fuzzy ...
Maoyin Zhang   +3 more
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

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