Results 131 to 140 of about 1,627,856 (332)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

HOMOMORPHISM IN ROUGH LATTICE

open access: yesJournal of New Theory, 2015
− In this paper, we introduce the concept of set-valued homomorphism of a lattice which isthe generalization of ordinary lattice homomorphism. We construct generalized rough lower and upperapproximations operators, by means of a set-valued mapping, which
Dipankar Rana, Sankar Kumar Roy
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Differential inclusions and exact penalties

open access: yesElectronic Journal of Differential Equations, 2015
The article considers differential inclusion with a given set-valued mapping and initial point. It is required to find a solution of this differential inclusion that minimizes an integral functional.
Alexander V. Fominyh   +2 more
doaj  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Common Solutions of an Iterative Scheme for Variational Inclusions, Equilibrium Problems, and Fixed Point Problems

open access: yesJournal of Inequalities and Applications, 2009
We introduce an iterative scheme by the viscosity approximate method for finding a common element of the set of solutions of a variational inclusion with set-valued maximal monotone mapping and inverse strongly monotone mappings, the set of solutions of
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Convergence Results for Contractive Type Set-Valued Mappings

open access: yesAxioms
In this work, we study an iterative process induced by a contractive type set-valued mapping in a complete metric space and show its convergence, taking into account computational errors.
Alexander J. Zaslavski
doaj   +1 more source

Lyusternik-Graves Theorems for the Sum of a Lipschitz Function and a Set-valued Mapping

open access: yesSIAM Journal of Control and Optimization, 2016
R. Cibulka, A. Dontchev, V. Veliov
semanticscholar   +1 more source

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