Results 131 to 140 of about 6,189,727 (240)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Singapore 1:25,000 road map [cartographic material] /

open access: yes, 2010
Planimetric map of Singapore showing selected buildings, points of interest, and schools.; Some sheets include insets.; Includes list of schools.
Singapore. Ministry of Defence. Mapping Unit.
core  

Common Solutions of an Iterative Scheme for Variational Inclusions, Equilibrium Problems, and Fixed Point Problems

open access: yesJournal of Inequalities and Applications, 2008
We introduce an iterative scheme by the viscosity approximate method for finding a common element of the set of solutions of a variational inclusion with set-valued maximal monotone mapping and inverse strongly monotone mappings, the set of solutions of ...
Shyu DavidS   +3 more
doaj  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

A projective splitting algorithm for solving generalized mixed variational inequalities

open access: yesJournal of Inequalities and Applications, 2011
In this paper, a projective splitting method for solving a class of generalized mixed variational inequalities is considered in Hilbert spaces. We investigate a general iterative algorithm, which consists of a splitting proximal point step followed by a ...
Zou Yun-zhi, Xia Fu-quan
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

On a lower continuity of upper continuous mappings with values in the Sorgenfrey line(in Ukrainian)

open access: yesМатематичні Студії, 2013
We shown that for each lower continuous finite valued mapping from metrizable topological space $X$ inSorgenfrey line the set of points of upper continuous is residual in $X$.
O. V. Maslyuchenko   +2 more
doaj  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Map of Norfolk Island [cartographic material] : Drawn and reproduced by the National Mapping Office, Dept. of the Interior.

open access: yes, 1956
Relief shown by spot heights and contours. Contour at 100 ft.; "NMO/56/50"; Also available online http://nla.gov.au/nla.map-vn1758341.
Australia. National Mapping Office.
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

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