Results 51 to 60 of about 43,497 (213)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

ϵ-Henig Saddle Points and Duality of Set-Valued Optimization Problems in Real Linear Spaces

open access: yesThe Scientific World Journal, 2013
We study ϵ-Henig saddle points and duality of set-valued optimization problems in the setting of real linear spaces. Firstly, an equivalent characterization of ϵ-Henig saddle point of the Lagrangian set-valued map is obtained.
Zhi-Ang Zhou
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Fixed Point Theorems for Set-Valued Contraction Type Maps in Metric Spaces

open access: yesFixed Point Theory and Applications, 2010
We first give some fixed point results for set-valued self-map contractions in complete metric spaces. Then we derive a fixed point theorem for nonself set-valued contractions which are metrically inward.
O'Regan D, Amini-Harandi A
doaj   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

On The Integral Representation of Strictly Continuous Set-Valued Maps

open access: yesInternational Journal of Analysis and Applications, 2015
Let T be a completely regular topological space and C(T) be the space of bounded, continuous real-valued functions on T. C(T) is endowed with the strict topology (the topology generated by seminorms determined by continuous functions vanishing at in_nity)
Anaté K. Lakmon, Kenny K. Siggini
doaj   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Coincidence Point, Best Approximation, and Best Proximity Theorems for Condensing Set-Valued Maps in Hyperconvex Metric Spaces

open access: yesFixed Point Theory and Applications, 2008
In hyperconvex metric spaces, we first present a coincidence point theorem for condensing set-valued self-maps. Then we consider the best approximation problem and the best proximity problem for set-valued mappings that are condensing. As an application,
Farajzadeh AP   +3 more
doaj  

Generalized Contractive Set-Valued Maps on Complete Preordered Quasi-Metric Spaces

open access: yesJournal of Function Spaces and Applications, 2013
By using a suitable modification of the notion of a w-distance we obtain some fixed point results for generalized contractive set-valued maps on complete preordered quasi-metric spaces.
J. Marín, S. Romaguera, P. Tirado
doaj   +1 more source

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