Results 161 to 170 of about 925,039 (306)

The non-covered set in Dvoretzky covering is a set of multiplicity

We prove that the non-covered set in Dvortezky random covering is a set of multiplicity, by showing that the natural multiplicative chaotic measure is a Rajchman measure.
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Geo Spatial Assessment of Flood Hazard in Jhang District, Pakistan

, 2017
Floods are one of the leading natural disasters in Pakistan. In recent decades the frequency and intensity of floods has increased due to human and environmental factors.
Maryam Khalid, null Azeem Sultan, null Muhammad Nasar-u-Minallah, null Maryam Khalid, Muhammad Naeem Hassan, Omar Riaz, Muhammad Nasar-u-Minallah, Azeem Sultan, null Muhammad Naeem Hassan, null Omar Riaz   +9 more
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

A GSD ESTIMATION OF THE RELATIVE WORTH OF COVER CROPS IN COTTON PRODUCTION SYSTEMS

Cover crops can help reduce the negative environmental impacts of cotton production. Using time series yield data, this study utilizes generalized stochastic dominance to evaluate the relative worth, via risk premiums, of three cover crop and two ...
Millhollon, E.P., Paxton, Kenneth W., Giesler, G. Grant   +2 more
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Solving Set Cover with Pairs Problem using Quantum Annealing. [PDF]

Sci Rep, 2016
Cao Y, Jiang S, Perouli D, Kais S.
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

A New and Fast Approximation Algorithm for Vertex Cover Using a Maximum Independent Set (VCUMI)

Operations Research and Decisions, 2015
The importance of non-deterministic polynomial (NP) problems in real world scenarios has compelled researchers to consider simple ways of finding approximate solutions to these problems in polynomial time.
Imran Khan, Naveed Riaz
doaj