Results 51 to 60 of about 1,486,783 (327)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
About a certain NP complete problem
, 2020 In this article we introduce the concept of special decomposition of a set and the concept of special covering of a set under such a decomposition. We study the conditions for existence of special coverings of the sets, under the special decomposition of
Margaryan, Stepan
core
On the Optimality of a Class of LP-based Algorithms [PDF]
, 2009 In this paper we will be concerned with a class of packing and covering problems which includes Vertex Cover and Independent Set. Typically, one can write an LP relaxation and then round the solution.
Kumar, Amit +3 more
core +2 more sources
On the set multi-cover problem in geometric settings
Proceedings of the twenty-fifth annual symposium on Computational geometry, 2009 We consider the set multi-cover problem in geometric settings. Given a set of points P and a collection of geometric shapes (or sets) F, we wish to find a minimum cardinality subset of F such that each point p in P is covered by (contained in) at least d(p) sets. Here d(p) is an integer demand (requirement) for p.
Chekuri, Chandra +2 more
openaire +2 more sources
A Novel Approach to Combinatorial Problems: Binary Growth Optimizer Algorithm
BiomimeticsThe set-covering problem aims to find the smallest possible set of subsets that cover all the elements of a larger set. The difficulty of solving the set-covering problem increases as the number of elements and sets grows, making it a complex problem for
Dante Leiva +4 more
doaj +1 more source
Journal of Mathematics, 2021 Multigranulation rough set theory is an important tool to deal with the problem of multicriteria information system. The notion of fuzzy β-neighborhood has been used to construct some covering-based multigranulation fuzzy rough set (CMFRS) models through
Zaibin Chang, Lingling Mao
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
A study on exponential-size neighborhoods for the bin packing problem with conflicts
, 2017 We propose an iterated local search based on several classes of local and large neighborhoods for the bin packing problem with conflicts. This problem, which combines the characteristics of both bin packing and vertex coloring, arises in various ...
Capua, Renatha +3 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source