Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Metrically differentiable set-valued functions and their local linear approximants [PDF]
Alona Mokhov, Nira Dyn, Elza Farkhi
openalex +1 more source
Traces of functions from H? $$(\mathbb{B}^n )$$ on certain sets of hyperplanes [PDF]
, 1987 N. A. Shirokov
openalex +1 more source
Influence of a Set of Variables on a Boolean Function [PDF]
, 2023 Aniruddha Biswas, Palash Sarkar
openalex +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Discrete Dynamical System generated by set-valued function in metric spaces [PDF]
Mohamad Muslikh, Sa’adatul Fitri
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Clinical Interventions of Social Humanoid Robots in the Treatment of a Set of High- and Low-Functioning Autistic Iranian Twins [PDF]
, 2017 Alireza Taheri +3 more
openalex +1 more source
λ−Wijsman Weak Statistical Convergence of Sequences of Sets in Connection With Modulus Functions [PDF]
, 2023 Ibrahim S. Ibrahim +2 more
openalex +1 more source