Results 31 to 40 of about 173,457,374 (299)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Digitomotography in Parkinson's disease: a cross-sectional and longitudinal study. [PDF]
PLoS ONE, 2015 Motor symptoms in Parkinson's disease (PD) are usually assessed with semi-quantitative tests such as the Unified PD Rating Scale (UPDRS) which are limited by subjectivity, categorical design, and low sensitivity. Particularly bradykinesia as assessed e.g.
Walter Maetzler +5 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Polarization Observables T and F in single π0- and η-Photoproduction off quasi-free Nucleons
EPJ Web of Conferences, 2014 Meson photoproduction has developed into a powerful tool to study the nucleon excitation spectrum and test effective quark models which operate in the non-perturbative regime of QCD. An insight into the JP configurations and isospin decompositions of the
Strub Thomas
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
On Methodology of TAPs in Translation Process [PDF]
, 2021 In recent years, scholars have shifted from the study of translation products to the study of translation process, that is, to explore the psychological activities of translators in the process of translation in order to uncover how the human brain ...
ZHAO, Yushan
core +1 more source
Addiction Science & Clinical Practice, 2021 Background The treatment capacity for opioid use disorder (OUD) lags far behind the number of patients in need of treatment. Capacity is limited, in part, by the limited number of physicians who offer office based OUD treatment with buprenorphine ...
Adriane M. dela Cruz +4 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Whitman, Walt. Drum Taps: The Complete Civil War Poems; Drum-Taps: The Complete 1865 Edition [review] [PDF]
, 2016 Review of Whitman, Walt. Drum Taps: The Complete Civil War Poems. Introduction by James McPherson; Whitman, Walt. Drum-Taps: The Complete 1865 Edition, ed.
O\u27Neil, Brandon J +1 more
core +1 more source