Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Permutation-Based Distances for Groups and Group-Valued Time Series. [PDF]
Amigó JM, Dale R.
europepmc +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Extended Divergence-Measure Fields, the Gauss-Green Formula and Cauchy Fluxes. [PDF]
Chen GG, Irving C, Torres M.
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
A Dynamic Hybrid Weighting Framework for Teaching Effectiveness Evaluation in Multi-Criteria Decision-Making: Integrating Interval-Valued Intuitionistic Fuzzy AHP and Entropy Triggering. [PDF]
Lu C, Zhang Y.
europepmc +1 more source
Positive and negative experiences and emotions of older patients before, during and after hospital admission: patient journey mapping. [PDF]
Wagenaar B, Merten H, Wagner C.
europepmc +1 more source
From chaos to clarity: schema-constrained AI for auditable biomedical evidence extraction from full-text PDFs. [PDF]
Mortezaagha P +3 more
europepmc +1 more source
Topological Signal Processing from Stereo Visual SLAM. [PDF]
Salvo ED +4 more
europepmc +1 more source

