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The settlement of disputes is commonly seen as one of the principal function of modern international law. This chapter offers a structured overview of the analytical issues relating to the involvement of cities in international dispute settlement, which has itself taken a functionalist turn in recent decades.
openaire +2 more sources
Influence of Mortar Rheology on Aggregate Settlement [PDF]
The influence of the rheology of fresh concrete on the settlement of aggregate is examined. Fresh concrete exhibits a yield stress that, under certain conditions, prevents the settlement of coarse aggregate, although its density is larger than that of ...
Gadala-Maria, Francis+4 more
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Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric+11 more
wiley +1 more source
Foliar Application of Strontium for the Identification of Roots from Specific Wheat Plants
In the field of crop research, the study of roots involves many challenges, particularly the lack of effective methods for identifying crop roots. To deal with this problem, this study proposes a solution strategy: in applying strontium to crop leaves ...
Senlin Fu+4 more
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Recollections of the Early Settlement of North-Western Iowa (pt. 10) [PDF]
N. Levering
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Payment System Settlement and Bank Incentives [PDF]
In this paper we consider the relative merits of net versus gross settlement of interbank payments. Net settlement economizes on the costs of holding non-interest-bearing reserves, but increases moral hazard problems.
Charles M. Kahn, William Roberds
core
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source