Results 111 to 120 of about 486,584 (353)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Lairds of suburbia: Scottish migrant settlement and housing in Australian cities, 1880-1930

open access: yes, 2016
Drawing on decennial population statistics from 1881 to 1933, this article evaluates the settlement patterns of Scottish migrants in Australian cities.
Wilkie, Ben
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Consumer Financing Dispute Settlement Patterns During the Covid-19 Pandemic in Wetland Environments

open access: hybrid, 2022
Zakiyah Zakiyah   +4 more
openalex   +1 more source

Settlement Patterns on the Swedish Countryside in the Emerging Knowledge Society [PDF]

open access: yes
As in other countries, urbanization and industrialization in Sweden was two sides of the same coin. To a large extent, the Swedish urbanization took place at a low level with the emergence of many small towns.
Hans Westlund, Wolfgang Pichler
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Czy mamy juz w Polsce mala Ukraine i polskie Viettown? Spoleczno-przestrzenne wzory zamieszkiwania imigrantów w metropolii warszawskiej [PDF]

open access: yes, 2007
The text aims to analyse the patterns of immigrants" settlement in Warsaw agglomeration, especially their settlement in the area of the city of Warsaw.
Grzymała-Kazłowska , A., Piekut, A.
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

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