Frontiers in Medicine, 2021 Background: This meta-analysis aimed to assess the prognostic value of hyponatremia in patients with COVID-19.Methods: We performed a systematic literature search on PubMed, Scopus, ScienceDirect, and Wiley up until January 26, 2021. The key exposure was
Mohammad Rizki Akbar +6 more
doaj +1 more source
Severe pulmonary hypertension: data from the Swiss Registry [PDF]
, 2001 BACKGROUND: Severe pulmonary hypertension (PH) is a rare disease with a dismal prognosis if untreated. Progress in diagnosis and in the development of effective therapeutic options has created new interest in this pathology.
Speich, R +13 more
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Diminished Prolinemia in Chronic Chagasic Patients: A New Clue for Disease Pathology?
Molecules, 2019 Trypanosoma cruzi, the etiological agent of Chagas disease, is dependent on proline for a variety of processes, such as energy metabolism, host cell invasion, differentiation, and resistance to osmotic, metabolic, and oxidative stress.
Sandra Carla Rocha +4 more
doaj +1 more source
Diagnosing Severe Falciparum Malaria in Parasitaemic African Children: A Prospective Evaluation of Plasma PfHRP2 Measurement. [PDF]
, 2012 In African children, distinguishing severe falciparum malaria from other severe febrile illnesses with coincidental Plasmodium falciparum parasitaemia is a major challenge. P. falciparum histidine-rich protein 2 (PfHRP2) is released by mature sequestered
Pan-Ngum Wirichada +127 more
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SARS-CoV-2 neutralizing antibody responses are more robust in patients with severe disease
Emerging Microbes and Infections, 2020 We studied plasma antibody responses of 35 patients about 1 month after SARS-CoV-2 infection. Titers of antibodies binding to the viral nucleocapsid and spike proteins were significantly higher in patients with severe disease.
Pengfei Wang +17 more
doaj +1 more source
Parvovirus B19 infection and severe anaemia in Kenyan children: a retrospective case control study [PDF]
, 2010 Background: During acute Human parvovirus B19 (B19) infection a transient reduction in blood haemoglobin concentration is induced, due to a 5-7 day cessation of red cell production.
James Wildig +21 more
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Hematological Parameters in Severe Complicated Plasmodium falciparum Malaria among Adults in Aden
Turkish Journal of Hematology, 2013 OBJECTIVE: To study some hematological parameters in adult patients with complicated severe malaria and their relations to clinical outcome. METHODS: This was a prospective study, including 77 patients from Aden Governorate with complicated severe ...
Sawsan Bakhubaira
doaj +1 more source
Role of biomarkers in prognostication of moderate and severe COVID-19 cases
Journal of Family Medicine and Primary Care, 2023 Background: COVID-19 pandemic demanded upgrading of laboratory medicine to limit morbidity, disability and mortality from moderate and severe SARS-COV-2 infections. Objective: To assess among moderate and severe COVID-19 patients, C-reactive protein (CRP)
Santasmita Pal +4 more
doaj +1 more source
Molecular mechanisms of severe acute respiratory syndrome (SARS) [PDF]
, 2005 Severe acute respiratory syndrome (SARS) is a new infectious disease caused by a novel coronavirus that leads to deleterious pulmonary pathological features.
David A Groneberg +6 more
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Assessment of severe malaria in a multicenter, phase III, RTS, S/AS01 malaria candidate vaccine trial: case definition, standardization of data collection and patient care. [PDF]
, 2011 BACKGROUND\ud \ud An effective malaria vaccine, deployed in conjunction with other malaria interventions, is likely to substantially reduce the malaria burden. Efficacy against severe malaria will be a key driver for decisions on implementation.
Amanda Leach +56 more
core +1 more source