Results 71 to 80 of about 206,088 (262)

Operationalizing BioSSbD: A safe‐and‐sustainable‐by‐design framework for biorefineries

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Biorefineries are central to the transition toward a circular bioeconomy; however, their increasing scale and technological heterogeneity, and the integration of biological, chemical, and thermochemical processes introduce complex challenges related to safety, sustainability, and operational reliability. Existing Safe‐and‐Sustainable‐by‐Design
Fernando Ramonet
wiley   +1 more source

SEAKNOT: LOOKING AHEAD OF SEVERE ACCIDENT RESEARCH

Severe Accidents (SAs) dominate the risk associated to the commercial production of nuclear energy. Despite the major achievements made in their research, still existing gaps, upcoming new technologies as Accident Tolerant Fuels (ATFs) and Small Modular ...
S. Gupta, S. Paci, L. E. Herranz, P. Piluso   +3 more
core  

Home accidents amongst elderly people: A locality study in Scotland

, 2007
Aim The aim of this locality study was to collect information on reported and unreported accidents amongst elderly people living in one locality in Scotland.
Dunleavy, K, Banks, P, Gilhooly, M, Barrett, W, MacDonald, C, Caldwell, S, Wales, A   +6 more
core  

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

UNIPI Research Activities in the Field of Severe Accident Mitigation

, 2016
During an accident involving a core melt at a LWR, radioactive elements emitted from fuel rods may be released into the environment. For many years UNIPI has contributed to research projects that aim to improve our understanding of the evolution of core ...
Sandro Paci
core  

Enhancing severe accident management through research

After the Fukushima Daiichi accident, a new wave of research projects aiming at enhancing severe accident (SA) management was launched under different international frameworks. This was the case of MUSA (Management and Uncertainties of Severe Accidents),
Luis E. Herranz, Kärkelä, Teemu, Jiménez, Gonzalo, Teemu Kärkelä, Herranz, Luis E., Gonzalo Jiménez   +5 more
core   +1 more source

Severe accident issue resolution -- definition and perspective [PDF]

, 1995
The purpose of this discussion is to introduce the session on the Progress on the Resolution of Severe Accident Issues. There has been much work in the area of resolution of severe accident issues over the past few years.
Harper, F. T.
core  

Supratherapeutic drug concentration triggers: A novel data‐driven approach to assess their value for medication safety surveillance in intensive care

British Journal of Clinical Pharmacology, EarlyView.
Aims Electronic triggers (e‐triggers) are used as screening signals to detect potential adverse drug events (ADEs) and offer an effective system level approach for medication safety surveillance. Their clinical utility is typically evaluated through time‐consuming manual chart review by experts, limiting implementation.
Anne Paulien Langermans, Izak A. R. Yasrebi‐de Kom, Dylan Wayne de Lange, Nicolette Fransisca de Keizer, Joanna E. Klopotowska, on behalf of the RESCUE Study group, C. S. C. Bouman, E. N. van Roon, P. F. Schutte, J. ten Cate, D. van Balen, S. Hendriks, C. Lau, W. J. Vermeijden, A. Beishuizen, J. B. Masselink, P. E. Spronk, H. J. M. van Kan, P. W. de Feiter, E. J. Wils, A. Wieringa, A. J. Valkenburg, W. M. van den Bergh, M. H. Renes, W. Bult, E. de Jonge, M. Hoeksema, E. J. Wesselink, I. M. Purmer, B. E. Bosma, S. H. W. van Bree, H. J. W. Lammers, R. J. Bosman, E. J. F. Franssen, A. Karakus, M. Sigtermans, E. M. Kuck, D. A. Dongelmans, M. J. H. Aries, E. V. Uijtendaal, M. C. Reuland   +40 more
wiley   +1 more source

Severe and fatal car crashes due to roadside hazards: a report to the Motor Accident Commission

, 1999
The NHMRC Road Accident Research Unit (RARU) was funded by the Motor Accident Commission in 1997 to investigate the role of roadside hazards in road accidents resulting in death or serious injury to a car occupant in South Australia. The main aim of this
McLean, J., Cockington, A., Kloeden, C., Baldock, M.   +3 more
core  

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

British Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley, Sam Francis, John Reader, Judi Proctor   +3 more
wiley   +1 more source