Results 181 to 190 of about 1,086,050 (360)

Identification of a novel coronavirus in patients with severe acute respiratory syndrome.

New England Journal of Medicine, 2003
C. Drosten, S. Günther, W. Preiser, S. van der Werf, H. Brodt, S. Becker, H. Rabenau, M. Panning, L. Kolesnikova, R. Fouchier, A. Berger, A. Burguière, J. Cinatl, M. Eickmann, N. Escriou, Klaus Grywna, S. Kramme, J. Manuguerra, S. Müller, V. Rickerts, M. Stürmer, Simon Vieth, H. Klenk, A. Osterhaus, H. Schmitz, H. Doerr   +25 more
semanticscholar   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han, Chunsheng Wang, Xiuli Guo, Yuan Luo, Jianguo Zhang, Fajian He, Zihang Zeng, Jiang Luo, Wen Ouyang, Yan Gong, Conghua Xie   +10 more
wiley   +1 more source

Sotrovimab Resistance and Viral Persistence After Treatment of Immunocompromised Patients Infected With the Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant [PDF]

, 2022
Sammy Huygens, Bas B. Oude Munnink, Arvind Gharbharan, Marion Koopmans, Bart Rijnders   +4 more
openalex   +1 more source

Seipin‐Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu, Junxia Zhang, Yusi Chen, Geng Shen, Yufei Han, Zihao Zhou, Jinxuan Chen, Xuya Kang, Huilin Qu, Jiaxin Duanmu, Haibao Shang, Yingjia Li, Wei Huang, Yan Zhang   +13 more
wiley   +1 more source

Impact of Severe Acute Respiratory Syndrome Coronavirus 2 Variants on Inpatient Clinical Outcome [PDF]

, 2022
Matthew L. Robinson, C. Paul Morris, Joshua Betz, Yifan Zhang, Robert C. Bollinger, Natalie Wang, David R. Thiemann, Amary Fall, Raghda E. Eldesouki, Julie M. Norton, David C. Gaston, Michael Forman, Chun Huai Luo, Scott L. Zeger, Amita Gupta, Brian T. Garibaldi, Heba H. Mostafa   +16 more
openalex   +1 more source

Site‐Specific Mitochondrial RNA N1‐Methyladenosine Demethylation via an Engineered MTS‐PUF‐ALKBH3 Fusion Protein

Advanced Science, EarlyView.
A CRISPR‐free mitochondrial RNA m1A demethylation (MRD) editor combining MTS, PUF proteins, and ALKBH3 enables precise m1A removal from mitochondrial mRNA and tRNA, which influences mitochondrial protein levels, cellular proliferation, ATP production, and mitochondrial respiration. Subsequently, in vivo demethylation of the m1A modification is achieved
Xiangrui Li, Deqiang Kong, Hongmei Liu, Jie Yang, Jiale Zhou, Yuqiang Qian, Ding Zhao, Jinze Li, Xinyu Wu, Tao Zhang, Xiaodi Sun, Yang Han, Liangxue Lai, Zhanjun Li   +13 more
wiley   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Advanced Science, EarlyView.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang   +3 more
wiley   +1 more source

Photobiomodulation Strengthens Muscles via Its Dual Functions in Gut Microbiota

Advanced Science, EarlyView.
Non‐invasive photobiomodulation therapy (PBMT) enhances muscle endurance by rewiring the gut‐muscle axis. PBMT preserves gut epithelial integrity and enriches beneficial anaerobes, driving metabolites such as butyrate, spermidine, and L‐carnitine that supercharge mitochondrial energy in skeletal muscles.
Prabhat Upadhyay, Asmita Banstola, Brijesh Bhayana, Mei X. Wu   +3 more
wiley   +1 more source

Comparative efficacy evaluation of disinfectants against severe acute respiratory syndrome coronavirus-2

, 2022
Lee G-H, So Hyun Park, B.-K. Song, Dae-Min Kim, Ho Jae Han, J-Y. Park, Y-W. Jo, M-Y. Hwang, K-T. Sim, S-M. Kang, Dongseob Tark   +10 more
openalex   +1 more source

Individualizing dialysis dose under certain circumstances during the Severe Acute Respiratory Syndrome Coronavirus-2 (coronavirus disease 2019) pandemic: a perspective [PDF]

, 2020
Tarek Samy Abdelaziz
openalex   +1 more source