Results 341 to 350 of about 569,433 (400)

Minimal Impact of Prior Common Cold Coronavirus Exposure on Immune Responses to Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination or Infection Risk in Older Adults in Congregate Care. [PDF]

Open Forum Infect Dis
Breznik JA, Cowbrough B, Bilaver L, Dushoff M, Stacey HD, Ang J, Clare R, Kennedy A, Costa AP, Nazy I, Loeb M, Verschoor CP, Bramson J, Miller MS, Bowdish DME, COVID in Long-Term Care investigator group .   +15 more
europepmc   +1 more source

Utility of BioFire FilmArray Pneumonia Panel Plus in a High‐Risk Cohort: Children Post Allogeneic Stem Cell Transplantation

Pediatric Blood &Cancer, Volume 72, Issue 10, October 2025.
ABSTRACT Introduction Pulmonary complications due to infection contribute significantly to post‐haematopoietic stem cell transplant (HCT) morbidity and mortality. Standard microbiological investigations, when performed on bronchoalveolar lavage (BAL) fluid, can take days to weeks to confirm a diagnosis.
Hannah Walker, Theresa Cole, Liam Gubbels, Helen Pham, Melanie Neeland, Diane Hanna, Vanessa Clifford, Shivanthan Shanthikumar, Gabrielle M. Haeusler   +8 more
wiley   +1 more source

Trajectories of Health-Related Quality of Life 2 Years After Mild/Moderate Severe Acute Respiratory Syndrome Coronavirus 2 Infection in the Pre-Omicron Era. [PDF]

Open Forum Infect Dis
Jacka BP, Cheng QL, Schiavone B, Darley DR, Kelleher AD, Dore GJ, Matthews GV.   +6 more
europepmc   +1 more source

Evaluating the protonation state of the catalytic Cys25 in cruzain cysteine protease: A target for Chagas disease

Protein Science, Volume 34, Issue 10, October 2025.
Abstract Cruzain (Cz), the major cysteine protease of Trypanosoma cruzi, the etiological agent of Chagas disease, employs Cys25 as its catalytic nucleophile, enabling peptide bond hydrolysis via nucleophilic attack on the carbonyl carbon of substrates.
Clauber H. S. da Costa, Vinícius Bonatto, Hemillin Brenda Teixeira Santos, Carlos Gabriel da Silva de Souza, Carlos A. Montanari, Munir S. Skaf, F. Javier Luque, Jerônimo Lameira   +7 more
wiley   +1 more source

Patients With Inflammatory Bowel Disease Are at Increased Risk of Respiratory Syncytial Virus Infections After Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Propensity-Matched Cohort Analysis. [PDF]

Clin Transl Gastroenterol
Alsakarneh S, Ramirez Ramirez O, Hayney MS, Hashash JG, Farraye FA, Caldera F.   +5 more
europepmc   +1 more source

Rational design of a covalent ACE2 decoy receptor that broadly neutralizes SARS‐CoV‐2 variants

Protein Science, Volume 34, Issue 10, October 2025.
Abstract The ongoing evolution of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and the emergence of variants that evade existing vaccines and antibody therapies necessitate novel, potent, and broad‐spectrum antiviral strategies. Enhancing therapeutic proteins with additional covalent binding capabilities, such as minibinders and ...
Nobumasa Hino, Risa Takada, Kyosuke Suzuki, Nagisa Tokunoh, Tatsuya Karaki, Kazumasa Ohtake, Haruna Ogami, Takafumi Nishiura, Kenji Ishimoto, Tomohito Tsukamoto, Yukio Ago, Yoshiaki Okada, Toru Okamoto, Chikako Ono, Yoshiharu Matsuura, Satoshi Obika, Kensaku Sakamoto, Yasuo Yoshioka, Shinsaku Nakagawa   +18 more
wiley   +1 more source

Effect of Universal Masking on Non-Severe Acute Respiratory Syndrome Coronavirus 2 Healthcare-Associated Respiratory Viral Infections. [PDF]

Open Forum Infect Dis
Munigala S, Ching PR, Wood H, Waken RJ, Fox J, Gasama H, Russell R, Yarbrough ML, Warren DK.   +8 more
europepmc   +1 more source

Phosphorylation Changes SARS‐CoV‐2 Nucleocapsid Protein's Structural Dynamics and Its Interaction With RNA

Proteins: Structure, Function, and Bioinformatics, Volume 93, Issue 10, Page 1701-1716, October 2025.
ABSTRACT The SARS‐CoV‐2 nucleocapsid protein, or N‐protein, is a structural protein that plays an important role in the SARS‐CoV‐2 life cycle. The N‐protein takes part in the regulation of viral RNA replication and drives highly specific packaging of full‐length genomic RNA prior to virion formation.
Stefan Loonen, Lina van Steenis, Marianne Bauer, Nikolina Šoštarić   +3 more
wiley   +1 more source

Steroid Pulse Therapy Leads to Secondary Infections and Poor Outcomes in Patients with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Intensive Care Units: A Retrospective Cohort Study. [PDF]

Viruses
Nakagawa K, Ihara S, Yamaguchi J, Kuwana T, Kinoshita K.   +4 more
europepmc   +1 more source

Intersectionality and Long Covid: Understanding the Lived Experiences of Ethnic Minority Groups in the United Kingdom

Health Expectations, Volume 28, Issue 5, October 2025.
ABSTRACT Introduction Long Covid is the patient‐preferred term to describe persistent symptoms experienced following an acute Covid‐19 infection. The severity and unpredictable nature of long Covid symptoms can affect every aspect of an individual's life.
Yojana Lotankar, Anna Cheshire, Damien Ridge, Carolyn Chew‐Graham, Nina Smyth, Claudia R. Knowles, Dipesh Gopal, Tom Kingstone, Shoba Dawson   +8 more
wiley   +1 more source