Identification and Development of Therapeutics for COVID-19 [PDF]
After emerging in China in late 2019, the novel Severe acute respiratory syndrome-like coronavirus 2 (SARS-CoV-2) spread worldwide and as of early 2021, continues to significantly impact most countries. Only a small number of coronaviruses are known to infect humans, and only two are associated with the severe outcomes associated with SARS-CoV-2 ...
arxiv +1 more source
COVID-19 : a matter close to the heart [PDF]
© This is an open-access article distributed under the terms of the Creative Commons Attribution License 4.0 International – CC BYThe world is facing a new challenge, the novel coronavirus disease 2019 (COVID-19), caused by a betacoronavirus named severe
Oliveira, Gláucia Maria Moraes de+1 more
core +2 more sources
Lack of Effectiveness of Repurposed Drugs for COVID-19 Treatment [PDF]
The magnitude of the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has prompted the repurposing of several drugs to quickly stop the morbidity, mortality, and spread of this new ...
Martinez, Miguel Angel
core +1 more source
Severe acute respiratory syndrome coronavirus-2-associated cholangiopathies
Purpose of review SARS-CoV2 is a β-coronavirus, isolated for the first time in Wuhan in December 2019. Bilateral interstitial pneumonia is the hallmark of this disease. Liver is the second viral target for frequency and AST and ALT elevation is a common finding.
Bartoli A., Cursaro C., Andreone P.
openaire +3 more sources
Findings of Hepatic Severe Acute Respiratory Syndrome Coronavirus-2 Infection [PDF]
Liver injury due to coronavirus disease 2019 (COVID-19) is being increasingly recognized. Abnormal liver chemistry tests of varying severities occur in a majority of patients. However, there is a dearth of accompanying liver histologic studies in these patients.The current report details the clinical courses of 2 patients having severe COVID-19 ...
Fiel, M. Isabel+11 more
openaire +4 more sources
Broad-Spectrum Antivirals against Multiple Human and Animal Coronaviruses Infection
Among the seven coronaviruses that infect humans, HCoV-229E, HCoV-OC43, HCoV-NL63, and HCoV-HKU1 usually cause mild and common cold symptoms; however, infection with three coronaviruses, namely severe acute respiratory syndrome coronavirus [SARS-CoV ...
Divyasha Saxena+2 more
doaj +1 more source
Severe acute respiratory syndrome coronavirus 2 seroprevalence among patients with pulmonary tuberculosis [PDF]
Objective: The objective of this study was to estimate the seroprevalence of severe acute respiratory syndrome coronavirus 2 antibodies in patients with tuberculosis.
Barbosa, Márcia Silva+4 more
core
An organoid-derived bronchioalveolar model for SARS-CoV-2 infection of human alveolar type II-like cells [PDF]
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which may result in acute respiratory distress syndrome (ARDS ...
Beumer, J. (Joep)+19 more
core +3 more sources
Objectives: Recent studies after the outbreak of coronavirus disease 2019 have shown an association of the ABO blood group to the susceptibility of severe acute respiratory syndrome coronavirus 2 infection.
Sanyukta Gurung+8 more
doaj +1 more source
Presentation of Severe Acute Respiratory Syndrome-Coronavirus 2 Infection as Cholestatic Jaundice in Two Healthy Adolescents [PDF]
© 2020 Elsevier Inc. Liver abnormalities in severe acute respiratory syndrome-coronavirus 2 infection, including hepatitis and cholestasis, have been observed in adults and are associated with worse outcomes.
Ahuja, K. L.+5 more
core +2 more sources