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After the outbreak of the severe acute respiratory syndrome (SARS) in the world in 2003, human coronaviruses (HCoVs) have been reported as pathogens that cause severe symptoms in respiratory tract infections.
Jiabao Xu +7 more
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Review on development of potential inhibitors of SARS-CoV-2 main protease (MPro)
Background The etiological agent for the coronavirus illness outbreak in 2019–2020 is a novel coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (COVID-19), whereas coronavirus disease pandemic of 2019 (COVID-19) has ...
Soumya Gulab Katre +6 more
doaj +1 more source
Genetic lesions within the 3a gene of SARS-CoV [PDF]
A series of frameshift mutations within the 3a gene has been observed in culture-derived severe acute respiratory syndrome coronavirus (SARS-CoV).
Barkham, Timothy +7 more
core +3 more sources
Severe Acute Respiratory Syndrome (SARS) [PDF]
The outbreak of SARS (2002-2003) makes an interesting case study which illustrates the nexus of infectious disease and global security. Four aspects of the epidemic are particularly significant: the character of the newly emergent pathogen, the unprecedentedly rapid tempo of its worldwide spread, the transformed global public health context in which it
openaire +2 more sources
Case Report: A Severe Paediatric Presentation of COVID-19 in APDS2 Immunodeficiency
Critical respiratory manifestations of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) are rare in children, and little is known about how immunocompromised children respond to the infection.
Nuria Sanchez Clemente +7 more
doaj +1 more source
Coronavirus 2019 (COVID-19) is an infectious viral illness caused by severe acute respiratory syndrome virus coronavirus 2 (SARS-CoV-2). This disease mainly affects the lungs manifesting as acute lung injury, pneumonia, and acute respiratory distress ...
Monique Oye +3 more
doaj +1 more source
COVID-19: a new turning point for dental practice [PDF]
Recent new zoonotic respiratory viruses have infected humans and led to severe acute respiratory syndrome: severe acute respiratory syndrome coronavirus (SARS-CoV), influenza A H5N1, influenza A H1N1 and Middle East respiratory syndrome coronavirus (MERS-
Flávio Freitas MATTOS +1 more
doaj +2 more sources
The 2019 novel coronavirus (officially known as severe acute respiratory syndrome coronavirus 2, SARS-CoV2) was first found in Wuhan, China. On February 11, 2020, the World Health Organization (WHO) has declared the outbreak of the disease caused by SARS-
Saeid Safari +8 more
doaj +1 more source
Understanding Viral Transmission Behavior via Protein Intrinsic Disorder Prediction: Coronaviruses [PDF]
Besides being a common threat to farm animals and poultry, coronavirus (CoV) was responsible for the human severe acute respiratory syndrome (SARS) epidemic in 2002-4. However, many aspects of CoV behavior, including modes of its transmission, are yet to
Dunker, A. Keith +2 more
core +3 more sources
Modernising epidemic science: enabling patient-centred research during epidemics [PDF]
Background: Emerging and epidemic infectious disease outbreaks are a significant public health problem and global health security threat. As an outbreak begins, epidemiological investigations and traditional public health responses are generally mounted ...
Horby, Peter W., Rojek, Amanda M.
core +3 more sources

