Results 71 to 80 of about 484,319 (306)

Perspective of molecular immune response of SARS-COV-2 infection

Jurnal Teknologi Laboratorium, 2020
COVID-19 is a type of Pneumonia caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). When COVID-19 arise in Wuhan China and rapidly spread throughout to the World, we need to learn how pathogenesis and immune responses occur in the ...
Martina Kurnia Rohmah, Arif Rahman Nurdianto   +1 more
doaj   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Central nervous system complications associated with SARS-CoV-2 infection: integrative concepts of pathophysiology and case reports

Journal of Neuroinflammation, 2020
Coronavirus disease 2019 (COVID-19) is a highly infectious pandemic caused by a novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Souhel Najjar, Amanda Najjar, Derek J. Chong, Bidyut K. Pramanik, Claudia Kirsch, Ruben I. Kuzniecky, Steven V. Pacia, Salman Azhar   +7 more
doaj   +1 more source

Label‐Free Sensing of Coronaviral Sequences via Kretschmann‐Configuration Reflectance Spectroscopic Ellipsometry: Sensitivity, Specificity, and Interfacial Effects

Advanced Materials Interfaces, EarlyView.
Spectroscopic ellipsometry in the Kretschmann‐Raether configuration (KRSE) is employed to characterize a DNA‐functionalized platform for viral sequence recognition. By merging SE with surface plasmon resonance, KRSE outperforms conventional SE, achieving nanomolar targeting through resonance wavelength shifts (δλ) measurements. Its enhanced interfacial
Silvia Maria Cristina Rotondi, Paolo Canepa, Francesco Bisio, Ornella Cavalleri, Maurizio Canepa   +4 more
wiley   +1 more source

Intestinal Microbiota Composition of Children with Infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) and Multisystem Inflammatory Syndrome (MIS-C) [PDF]

, 2022
Cansu Suskun, Ömer Kılıç, Dilek Yılmaz Çiftdoğan, Şirin Güven, Adem Karbuz, Aslınur Özkaya Parlakay, Yalçın Kara, Ebru Kaçmaz, Aslıhan Şahin, Aysun BOGA, Didem Kızmaz İşançlı, Belgi̇n Gülhan, Saliha Kanık Yüksek, Eylem Kıral, Gürkan Bozan, Mehmet Özgür Arslanoğlu, Mahmut Can Kızıl, Meltem Dinleyici, Tercan Us, Ahmet Variş, Mücahit Kaya, Yvan Vandenplas, Ener Çağrı Dinleyici   +22 more
openalex   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Mathematical modeling of the spread of the coronavirus under strict social restrictions

Mathematical Methods in the Applied Sciences, EarlyView., 2021
We formulate a simple susceptible‐infectious‐recovery (SIR) model to describe the spread of the coronavirus under strict social restrictions. The transmission rate in this model is exponentially decreasing with time. We find a formula for basic reproduction function and estimate the maximum number of daily infected individuals.
Mo'tassem Al‐arydah, Hailay Berhe, Khalid Dib, Kalyanasundaram Madhu   +3 more
wiley   +1 more source

A 5-Lipoxygenase Inhibitor, Zileuton, Modulates Host Immune Responses and Improves Lung Function in a Model of Severe Acute Respiratory Syndrome (SARS) Induced by Betacoronavirus. [PDF]

Viruses, 2023
Pereira RDD, Rabelo RAN, Oliveira NFM, Porto SLT, Andrade ACDSP, Queiroz-Junior CM, Barbosa CLN, de Souza-Costa LP, Santos FRDS, Oliveira FBR, da Silva BLV, Umezu HL, Ferreira R, da Silva GSF, Cruz JS, Teixeira MM, Costa VV, Machado FS.   +17 more
europepmc   +2 more sources

COVID-19: A Multidisciplinary Review

Frontiers in Public Health, 2020
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that is responsible for the 2019–2020 pandemic. In this comprehensive review, we discuss the current published literature surrounding the SARS-CoV-2 virus. We examine the
Nour Chams, Sana Chams, Reina Badran, Ali Shams, Abdallah Araji, Mohamad Raad, Sanjay Mukhopadhyay, Edana Stroberg, Eric J. Duval, Lisa M. Barton, Inaya Hajj Hussein   +10 more
doaj   +1 more source

Utility of Fear Severity and Individual Resilience Scoring as a Surge Capacity, Triage Management Tool during Large-Scale, Bio-event Disasters [PDF]

, 2006
Threats of bioterrorism and emerging infectious disease pandemics may result in fear related consequences. Fear based signs and symptoms, if left undetected and untreated, may be extremely debilitating and lead to chronic problems with risk of permanent ...
Bracha, H. Stefan, Burkle Jr., Frederick M.   +1 more
core   +1 more source