Results 71 to 80 of about 59,301 (217)

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source

Characterization of Pulmonary Functional Abnormalities in Systemic Sclerosis Using Xenon MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Xenon MRI is increasingly used to evaluate patients with interstitial lung disease (ILD) and pulmonary hypertension (PH), both of which are common manifestations of systemic sclerosis (SSc). As such, Xe‐MRI may be suited to interrogate lung function impairment in SSc.
Dawson Shaver, Steven Haworth, Evan Graumann, Bradie Frizzell, David H. Lee, Jiwoong Choi, Chase S. Hall, Scott M. Matson, Mark Hamblin, Mario Castro, Paul S. Schmidt, Peter J. Niedbalski   +11 more
wiley   +1 more source

Derivation and validation of a model to predict treatment failure among under five children with severe community acquired pneumonia who are admitted at Debre Tabor specialized comprehensive hospital.

PLoS ONE
BackgroundSevere community-acquired pneumonia related treatment failure is persistence of features of severe pneumonia after initiation of antimicrobial therapy or a worsening clinical condition within 48-72 hours of the commencement of the antibiotics ...
Muluken Chanie Agimas, Tigabu Kidie Tesfie, Nebiyu Mekonnen Derseh, Amare Kassaw   +3 more
doaj   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Post‐Omicron cognitive decline is largely reversible: Two‐year multicenter cohort study of domain‐specific outcomes in hospitalized patients

Neuroprotection, EarlyView.
Earlier variants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2), including the original strain, Alpha and Delta, were linked to significant and persistent cognitive impairment. The long‐term cognitive impact of Omicron infection, however, has remained uncertain. This study shows that post‐Omicron cognitive decline is largely reversible,
Min Qiu, Mengwen Wang, Shengcai Chen, Wenbo Zuo, Jiashuo Lin, Luojinyun Wang, Senwei Tan, Quanwei He, Yanan Li, Huijuan Jin, Xuan Niu, Wanli Li, Fengguang Li, Ming Huang, Yan Wan, Bo Hu   +15 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source

Biomarkers for Lipid and Albumin Metabolism in Hospitalized Patients with Underlying Diseases and Community-Acquired Pneumonia Caused by Bacterial or SARS-CoV-2 Infection

Journal of Inflammation Research, 2023
Zheng Liu,1 Qian Wang,1 Hui Wang,1 Jing Li,1 Ying Yuan,2 Guo-zhen Yi1 1Department of Respiratory Medicine, the Petroleum Clinical Medical College of Hebei Medical University, Langfang, People’s Republic of China; 2Department of Respiratory Medicine, the ...
Liu Z, Wang Q, Wang H, Li J, Yuan Y, Yi GZ   +5 more
doaj  

Sepsis and Antibiotics in Extremely Preterm Infants: Early Empirical Treatment Was Common, While Late‐Onset Sepsis Accounted for Most Cases and Antibiotic Use

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim was to investigate the incidence of sepsis and use of antibiotics among extremely preterm infants, given the limited number of population‐based studies examining this. Methods This retrospective study in Eastern Denmark included all liveborn infants from 23 + 0 weeks/days to 27 + 6 weeks/days of gestation from 2019 to 21.
Anna Bjerager Arnesen, Nini Møller, Louise Dyrberg Vibede, Kristian Vestergaard, Sara Krøis Holm, Cæcilie Trier, Hristo Stanchev, Gholamreza Dayani, Ulrikka Nygaard, Bo Mølholm Hansen, Emma Malchau Carlsen   +10 more
wiley   +1 more source

Antimicrobial Resistance in Children With Bloodstream Infections: A Population‐Based Study in Stockholm, Sweden

Acta Paediatrica, EarlyView.
ABSTRACT Aim We retrospectively evaluated trends in antimicrobial resistance (AMR) in paediatric bloodstream infections and assessed changes in antimicrobial prescription patterns over a 20‐year period. Methods We analysed positive blood cultures from children admitted with suspected serious infection between 1998 and 2018.
Joachim Luthander, Rutger Bennet, Per Nydert, Margareta Eriksson, Christian G. Giske, Anna Nilsson   +5 more
wiley   +1 more source