Results 111 to 120 of about 59,308 (237)

Signatures of lower respiratory tract microbiome in children with severe community-acquired pneumonia using shotgun metagenomic sequencing

Journal of Microbiology, Immunology and Infection
Background: Severe community-acquired pneumonia was associated with high morbidity and mortality in children. However, species-level microbiome of lower airway was sparse, and we used shotgun metagenomic next-generation sequencing to explore microbial ...
Ting-Yu Yen, Ching Hsu, Ni-Chung Lee, Chao-Szu Wu, Hsin Wang, Kuan-Yi Lee, Chia-Ray Lin, Chun-Yi Lu, Mo-Li Tsai, Tzu-Yu Liu, Che Lin, Chien-Yu Chen, Luan-Yin Chang, Feipei Lai, Li-Min Huang   +14 more
doaj   +1 more source

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

Omadacycline successfully treated severe Legionella pneumonia after moxifloxacin treatment failure: Case series

Frontiers in Pharmacology
Legionella is a significant pathogen responsible for community-acquired pneumonia and, less commonly, for hospital-acquired pneumonia. Legionella pneumophila, the most prevalent species within the Legionella genus, accounts for 80%–90% of human ...
Biyun Li, Laiyu Liu, Fei Li, Chunmei He, Yuan Chen, Xiaodong Tian, Zhenyu Liu, Weizhen Zhang   +7 more
doaj   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Periodontitis as a Model for Inflammatory Uncoupling of Bone Remodeling

Journal of Periodontal Research, EarlyView.
Periodontitis can be viewed as a state of inflammatory uncoupling of bone remodeling, in which excessive osteoclast‐mediated resorption coexists with impaired bone formation. This review integrates emerging insights from osteoimmunology, osteocyte biology, mechanobiology, aging, and resolution pathways to position periodontitis as an accessible in vivo
Rafael Scaf de Molon, Sotirios Tetradis, Rolando Vernal, Fabio Renato Manzolli Leite, Thomas E. Van Dyke   +4 more
wiley   +1 more source

Dying in the Desired Location—Findings From the Canadian Longitudinal Study on Aging

Journal of the American Geriatrics Society, EarlyView.
Philip D. St John, Robert B. Tate, Scott Nowicki, Genevieve N. Thompson, Cara L. Brown, Kerstin S. Roger, Shahin Shoostari, Lauren E. Griffith   +7 more
wiley   +1 more source

Adverse outcomes between VMAT2 and anticholinergics in tardive dyskinesia: A target trial emulation

Psychiatry and Clinical Neurosciences, EarlyView.
Aim Vesicular monoamine transporter 2 (VMAT2) inhibitors have been approved for the treatment of tardive dyskinesia (TD), whereas anticholinergic agents are still widely used for this condition. This study aimed to compare the risk of major clinical adverse outcomes among patients with TD treated with VMAT2 inhibitors versus anticholinergic agents ...
Tien‐Wei Hsu, Chih‐Wei Hsu, Ping‐Tao Tseng, Yi‐Ya Fang, Chuo‐Yu Lee, Yu‐Hsuan Lin, Brendon Stubbs, Trevor Thompson, Andre F. Carvalho, Yu‐Chen Kao, Jen‐Ping Chen, Fu‐Chi Yang, Chia‐Kuang Tsai, Chih‐Sung Liang   +13 more
wiley   +1 more source

Recipient–Donor Sex Combinations and Posttransplant Infections: A Swiss Transplant Cohort Study

Transplant Infectious Disease, EarlyView.
In this cohort study of 5033 patients, only the recipient sex, in particularly kidney recipients, was independently associated with an increased risk of infections, when compared to males. These findings indicate that recipient–donor sex combination does not influence short‐term solid organ transplantation outcome.
Christian T. J. Magyar, Charlene P. Gretener, Jaromil Frossard, Katell Mellac, Daniel Sidler, David Reineke, Nicolas J. Mueller, Franz Immer, Christian van Delden, Oriol Manuel, Thorsten Krueger, Nina Khanna, Katia Boggian, Lara Beekman, Cédric Hirzel, Vanessa Banz, Swiss Transplant Cohort Study (STCS)   +16 more
wiley   +1 more source

Bridging the Gap Between General and Transplant Infectious Disease Practice

Transplant Infectious Disease, EarlyView.
ABSTRACT The population of iatrogenic immunocompromised individuals is steadily rising as we continue to improve in our ability to manage diseases, including cancer, autoimmune disease, and end‐organ dysfunction, with increasing access to novel agents and transplantation.
Jeremey Walker, Emily Eichenberger, Steven Pergam, Maricar Malinis, Andrea J. Zimmer   +4 more
wiley   +1 more source

Incidental Detection of Respiratory Viruses in Lung Transplant Donor‐Recipient Pairs: Exploratory Associations With Clinical Outcomes in a Post Hoc Analysis

Transplant Infectious Disease, EarlyView.
In 53 lung transplant donor‐recipient pairs, community‐acquired respiratory viruses were incidentally detected by syndromic PCR in 13.2% of donor and 20.8% of recipient bronchoalveolar lavages, with exploratory, unadjusted signals towards longer hospitalization and chronic lung allograft dysfunction.
Andrea Lombardi, Letizia Corinna Morlacchi, Giulia Renisi, Lorenzo Rosso, Jacopo Fumagalli, Patrizia Bono, Ilaria Righi, Valeria Rossetti, Arianna Liparoti, Cecilia Azzarà, Davide Mangioni, Laura Alagna, Anna Celotti, Claudia Alteri, Chiara Abbruzzese, Annapaola Callegaro, Francesco Blasi, Giacomo Grasselli, Mario Nosotti, Alessandra Bandera   +19 more
wiley   +1 more source