Systemic corticosteroids for severe community-acquired pneumonia: a narrative review of mechanisms and critical appraisal of recent trials in ICU. [PDF]
Eastwood B +9 more
europepmc +1 more source
Trends in Enterobacteriaceae Resistance Patterns: A Nine‐Year Retrospective Study From North Lebanon
ABSTRACT Background and Aims Antimicrobial resistance (AMR) in Enterobacteriaceae poses a critical threat to global health, particularly in regions where antibiotic misuse and limited surveillance prevail. Intensive care units (ICUs) act as focal points for resistance emergence and dissemination. This study aimed to evaluate long‐term resistance trends
Mazen Zaylaa +12 more
wiley +1 more source
Improved prediction value of the CURB-65 score combined with the platelet-to-lymphocyte ratio for mortality in emergency department patients with severe community-acquired pneumonia. [PDF]
Lv C, Liu S, Yan Y, Ye Y, Gao Y, Zhou M.
europepmc +1 more source
ABSTRACT Background and Objective Parapneumonic effusion refers to any pleural effusion secondary to pneumonia. Thoracic ultrasound is the imaging modality of choice for evaluating pleural effusion. This study aimed to assess the role of thoracic ultrasound, guided by a proposed algorithm and classification system, in the management of parapneumonic ...
Seyed Ali Nourbakhsh Kumeleh +12 more
wiley +1 more source
Comparison of targeted next-generation sequencing and conventional tests for pathogen detection in community-acquired and severe community-acquired pneumonia: a retrospective cohort study. [PDF]
Wang F +6 more
europepmc +1 more source
ABSTRACT Background Pneumococcus are often found in the respiratory tract of healthy people, especially children, and are a common cause of infections such as otitis media, sinusitis, conjunctivitis and community‐acquired pneumonia. In other cases, the bacteria can cause more serious conditions known collectively as invasive pneumococcal disease (IPD),
Pamela Di Giovanni +9 more
wiley +1 more source
Clinical characteristics and risk factors for severe community-acquired pneumonia in hospitalized children with human metapneumovirus infection in Shanghai: a retrospective cohort study. [PDF]
Liu L +5 more
europepmc +1 more source
Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang +10 more
wiley +1 more source
Corticosteroids in bacterial severe community-acquired pneumonia: lessons from recent trials. [PDF]
Nguyen TL +5 more
europepmc +1 more source
This study developed a simple, low‐cost scoring system using routine complete blood count (CBC) and derived immune‐inflammatory indicators (LYM%, PLT, PCT, and PLT × LYM) for early diagnosis of Mycoplasma pneumoniae pneumonia (MPP) in 1662 children. Age‐stratified analysis confirmed that key indicators remained significantly higher in the pneumonia ...
Quan Liu +5 more
wiley +1 more source

