Results 131 to 140 of about 6,974,500 (303)

Preexisting prediabetes and the severity of COVID-19

open access: yesPrimary Care Diabetes, 2021
Sathish, Thirunavukkarasu   +2 more
openaire   +4 more sources

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

open access: yesAdvanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang   +16 more
wiley   +1 more source

Phenome‐Wide Association Study of Severe COVID‐19 Genetic Risk Variants

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Jessica A. Regan   +6 more
doaj   +1 more source

Coronavirus disease 2019 (COVID-19) : update and information for long-term care facilities [PDF]

open access: yes
Date: Tuesday, March 17, 2020Time: 2:00 P.M. \u2013 3:00P.M. (Eastern Time)During this COCA Call, presenters will focus on current information about COVID-19 as it relates to long-term care facilities, including nursing homes.

core  

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

open access: yesAdvanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao   +6 more
wiley   +1 more source

Convergence of Plasmid‐Mediated tmexCD‐toprJ With Critical Resistance Genes Fuels Spread of Multidrug Resistant Bacteria

open access: yesAdvanced Science, EarlyView.
Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song   +9 more
wiley   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

open access: yesAdvanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu   +10 more
wiley   +1 more source

Outcomes of COVID-19 in 24 hospitalized liver transplant recipients: an observational study

open access: yesBMC Infectious Diseases
Background Although liver transplant (LT) recipients are considered a population at risk of severe features of coronavirus disease 2019 (COVID-19), data in this regard are scarce and controversial. In this study, we reported the outcome of 24 cases of LT
Amir M. Sadeghian   +7 more
doaj   +1 more source

Severe outcomes among patients with Coronavirus Disease 2019 (COVID-19) - United States, February 12 - March 16, 2020

open access: yes, 2020
CDC COVID-19 Response Team: Stephanie Bialek, CDC; Ellen Boundy, CDC; Virginia Bowen, CDC; Nancy Chow, CDC; Amanda Cohn, CDC; Nicole Dowling, CDC; Sascha Ellington, CDC; Ryan Gierke, CDC; Aron Hall, CDC; Jessica MacNeil, CDC; Priti Patel, CDC ...
CDC COVID-19 Response Team
core  

A Modular Variable Stiffness Co‐Bot System Achieving Tasks Flexibility and Contact Compliance

open access: yesAdvanced Science, EarlyView.
Bio‐inspired antagonistic compliance enables a modular rigid‐soft co‐bot platform with variable stiffness for safe human‐robot interaction (HRI): Standardized interfaces support application‐driven configurations with tailored DoFs, workspace, and stiffness range, making the system suited to HRI and low‐volume automation.
Wenlong Gaozhang   +6 more
wiley   +1 more source

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