Results 11 to 20 of about 4,527,439 (244)

Severe Cutaneous Adverse Drug Reaction [PDF]

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2017
Background: Cutaneous adverse drug eruption (CADR) are frequently found. A systematic review showed, the incidence of severe CADR (SCADR) ranging from 0-8%. Few studies have assessed the severe form of CADR, which has high mortality rate.
Damayanti Damayanti, Sylvia Anggraeni, Cita Rosita SP, Marsudi Hutomo, Hari Sukanto   +4 more
doaj   +3 more sources

ASSOCIATION BETWEEN CARBAMAZEPINE INDUCED SEVERE CUTANEOUS ADVERSE DRUG REACTION AND HLA POLIMORPHISMS

Malang Neurology Journal, 2016
Carbamazepine as an antiepileptic drug that is used widely and was known can cause severe cutaneous adverse drug reactions like SJS-TEN. These adverse drug reactions is known to be associated with some specific HLA polymorphism in European populations ...
Safrina Dewi Ratnaningrum
doaj   +2 more sources

When Skin Reactions Interrupt Bone Therapy: Severe Cutaneous Adverse Reaction to Romosozumab Leading to Treatment Discontinuation. [PDF]

Eur J Case Rep Intern Med
Background: Romosozumab is a sclerostin-inhibiting monoclonal antibody that is effective and safe for anabolic treatment in patients with osteoporosis. Its main adverse effects are local; the severity of these injection-site reactions in clinical trials ...
Rodriguez Arrieta LA, Rueda Galvis PA, Rueda Galvis MV, Pantoja Meneses SA, Yépes Rodriguez JM, Suarez Contreras FJ.   +5 more
europepmc   +2 more sources

Severe Cutaneous Adverse Drug Reactions: Presentation, Risk Factors, and Management. [PDF]

, 2018
PURPOSE OF STUDY Immune-mediated adverse drug reactions occur commonly in clinical practice and include mild, self-limited cutaneous eruptions, IgE-mediated hypersensitivity, and severe cutaneous adverse drug reactions (SCAR).
S. Shahzad Mustafa, Daniel Yerly, Mustafa, S Shahzad, Ostrov, David, Yerly, Daniel, Mustafa, S. Shahzad, David Ostrov   +6 more
core   +2 more sources

Multi-state model for predicting ocular progression in acute Stevens-Johnson syndrome/toxic epidermal necrolysis.

PLoS ONE, 2021
This study aimed to clarify the etiologic factors predicting acute ocular progression in SJS/TEN, and identify patients who require immediate and intensive ophthalmological treatment.
Fumie Kinoshita, Isao Yokota, Hiroki Mieno, Mayumi Ueta, John Bush, Shigeru Kinoshita, Hirohiko Sueki, Hideo Asada, Eishin Morita, Masanori Fukushima, Chie Sotozono, Satoshi Teramukai, Japanese Research Committee on Severe Cutaneous Adverse Reaction   +12 more
doaj   +1 more source

HLA-B*58:01 for allopurinol-induced cutaneous adverse drug reactions: Implication for clinical interpretation in Thailand

Frontiers in Pharmacology, 2016
Background: The aim of this study was to investigate the predisposition to different types of allopurinol-induced cutaneous adverse drug reactions (CADR), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) (SJS-TEN, n=13), drug ...
Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem, ํYaowaluck Hongkaew, Thawinee Jantararoungtong, Thawinee Jantararoungtong, Parnrat Kuntawong, Apichaya Puangpetch, Apichaya Puangpetch, Napatrupron Koomdee, Napatrupron Koomdee, Patompong Satapornpong, Patcharin Supapsophon, Jettanong Klaewsongkram, Jettanong Klaewsongkram, Ticha Rerkpattanapipat, Ticha Rerkpattanapipat   +16 more
doaj   +1 more source

The assessment of severe cutaneous adverse drug reactions

, 2022
Severe cutaneous adverse drug reactions include Stevens-Johnson syndrome, toxic epidermal necrolysis and acute generalised exanthematous pustulosis. These eruptions are a type of delayed hypersensitivity reaction and can be life-threatening.
Copaescu, AM, Trubiano, JA
core   +1 more source

Acute generalized exanthematous pustulosis induced by sulfasalazine: Uncommon presentation of a common culprit

Indian Journal of Rheumatology, 2022
Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse drug reaction caused by drugs in the majority of cases. It is characterized by the sudden onset of nonfollicular sterile pustules, papules, and edematous plaques on an ...
Deepak Vashisht, Parul Kamboj, Manoj Gopal Madakshira, Preema Sinha, Arun Hegde, Juhi Sharma   +5 more
doaj   +1 more source

Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients

Journal of Immunology Research, 2018
The HLA-B∗15:02 allele has been reported to have a strong association with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in Thai patients.
Chonlaphat Sukasem, Chonlawat Chaichan, Thapanat Nakkrut, Patompong Satapornpong, Kanoot Jaruthamsophon, Thawinee Jantararoungtong, Napatrupron Koomdee, Suthida Sririttha, Sadeep Medhasi, Sarawut Oo-Puthinan, Ticha Rerkpattanapipat, Jettanong Klaewsongkram, Pawinee Rerknimitr, Papapit Tuchinda, Leena Chularojanamontri, Napatra Tovanabutra, Apichaya Puangpetch, Wichai Aekplakorn   +17 more
doaj   +1 more source

A posteriori diagnosis of DRESS syndrome induced by diazoxide in a patient with an insulinoma: a case report and review of the literature

Frontiers in Medicine, 2023
The Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome can be potentially life-threatening. The diagnosis is sometimes difficult since the clinical manifestations may be incomplete or non-specific.
Najoua Lassoued, Najoua Lassoued, Wafa Alaya, Sondos Arfa, Mouna Korbi, Ines Lassoued, Soumaya Ben Amor, Fatma Zaouali, Zayneb Farhat, Jihen Chelly, Mohamed Habib Sfar   +10 more
doaj   +1 more source