Severe dengue categories as research endpoints-Results from a prospective observational study in hospitalised dengue patients. [PDF]
PLoS Neglected Tropical Diseases, 2020 Severe dengue was perceived as one clinical disease entity until the WHO 2009 classification stratified it into severe vascular leakage, severe bleeding, and severe organ dysfunction.
Kerstin D Rosenberger +8 more
doaj +3 more sources
PLoS Neglected Tropical Diseases, 2023 Establishing reliable early warning models for severe dengue cases is a high priority to facilitate triage in dengue-endemic areas and optimal use of limited resources.
Jingli Yang +4 more
doaj +2 more sources
Analysis of dengue cases according to clinical severity, São Luís, Maranhão, Brazil [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 2017 Severe dengue cases have increased in Brazil since 2001, with the first records in Maranhão dating back to 2002. The aim of this study was to determine the prevalence of severe dengue cases by age group and the possible risk factors.
José de Jesus Dias Júnior +5 more
doaj +6 more sources
Increasing Dengue Burden and Severe Dengue Risk in Bangladesh: An Overview. [PDF]
Trop Med Infect Dis, 2023 Dengue is a prevalent and rapidly spreading mosquito-borne viral disease affecting humans. The geographic range of dengue is expanding, and much like in many other tropical regions of the world, dengue has become a major public health issue in Bangladesh.
Kayesh MEH +3 more
europepmc +2 more sources
Clinical relevance and discriminatory value of elevated liver aminotransferase levels for dengue severity. [PDF]
PLoS Neglected Tropical Diseases, 2012 BACKGROUND: Elevation of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) is prominent in acute dengue illness. The World Health Organization (WHO) 2009 dengue guidelines defined AST or ALT ≥ 1000 units/liter (U/L) as a criterion for ...
Linda K Lee +5 more
doaj +5 more sources
Clinical signs and symptoms associated with WHO severe dengue classification: a systematic review and meta-analysis [PDF]
Emerging Microbes and Infections, 2021 The World Health Organization (WHO) introduced the new dengue classification in 2009. We aimed to assess the association of clinical signs and symptoms with WHO severe dengue classification in clinical practice.
Tha Pyai Htun +2 more
openalex +2 more sources
Cardiac tamponade in a patient with severe dengue fever [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2017 A 26-year-old postpartum female presented with symptoms characteristic of dengue fever on the 16th day of puerperium. On the third day of the illness, the patient presented a clinical picture consistent with shock. Tests determined primary infection with
Ana Isabel Vieira Fernandes +7 more
doaj +2 more sources
Understanding immunopathology of severe dengue: lessons learnt from sepsis [PDF]
, 2020 Endothelial dysfunction leading to vascular permeability and plasma leakage are characteristic features of severe dengue and sepsis. However, the mechanisms underlying these immune-pathologies remain unclear.
Aguilar Briseño, Alberto +2 more
core +2 more sources
Risk factors associated with death in Brazilian children with severe dengue: a case-control study [PDF]
Clinics, 2014 Objective: The purpose of this case-control study was to evaluate risk factors associated with death in children with severe dengue. Methods: The clinical condition of hospitalized patients with severe dengue who died (cases, n = 18) was compared with ...
Maria dos Remedios Freitas Carvalho Branco +12 more
doaj +7 more sources
Discovery and validation of circulating miRNAs for the clinical prognosis of severe dengue. [PDF]
PLoS Neglected Tropical Diseases, 2022 BackgroundEarly prognostic markers of severe dengue may improve case management and reduce dengue-related mortalities. This study aimed to identify circulating microRNAs (miRNAs) as biomarkers for predicting severe dengue.MethodologySerum samples from ...
Umaporn Limothai +13 more
doaj +2 more sources