How I treat thrombotic thrombocytopenic purpura and atypical haemolytic uraemic syndrome [PDF]
Thrombotic thrombocytopenic purpura (TTP) and atypical haemolytic uraemic syndrome (aHUS) are acute, rare life-threatening thrombotic microangiopathies that require rapid diagnosis and treatment.
Goodship, T, Scully, M
core +1 more source
Severe Fever with Thrombocytopenia Syndrome Presenting with Hemophagocytic Lymphohistiocytosis
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease caused by the newly discovered SFTS Bunyavirus, and there have been no case reports of SFTS patients presenting with hemophagocytic lymphohistiocytosis (HLH) in the English literature.
Jongmin Lee+6 more
openaire +3 more sources
Severe fever with thrombocytopenia syndrome-associated encephalopathy/encephalitis [PDF]
Severe fever with thrombocytopenia syndrome (SFTS) virus has a variety of central nervous system (CNS) manifestations. However, there are limited data regarding SFTS-associated encephalopathy/encephalitis (SFTSAE) and its mechanism.All patients with confirmed SFTS who underwent cerebrospinal fluid (CSF) examination due to suspected acute encephalopathy
Taeeun Kim+13 more
openaire +3 more sources
Feminization and severe pancytopenia caused by testicular neoplasia in a cryptorchid dog [PDF]
In this case report, a paraneoplastic syndrome caused by testicular neoplasia in a ten-year-old cryptorchid dog is described. Feminization and pancytopenia were observed, resulting from the testicular neoplastic production of estrogens.
Hebbelinck, Lien+3 more
core
Aplastic Crisis as Primary Manifestation of Systemic Lupus Erythematosus [PDF]
Aplastic crisis is an unusual feature of systemic lupus erythematosus (SLE). We report the case of a 54-year-old woman presenting with both (extravascular) Coombs-positive hemolytic anemia and laboratory findings of bone marrow hyporegeneration with ...
Alger M+23 more
core +1 more source
Lymphoid Malignancies in Ataxia–Telangiectasia: Experience with Novel Targeted Therapies
ABSTRACT Patients with ataxia–telangiectasia (AT) face unique challenges in managing lymphoid malignancies due to heightened sensitivity to chemotherapy and radiation, requiring alternative treatment strategies. This report presents three cases demonstrating the successful integration of targeted therapies: ibrutinib for diffuse large B‐cell lymphoma ...
Samanta Catueno+9 more
wiley +1 more source
Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group. [PDF]
Cancer immunotherapy has transformed the treatment of cancer. However, increasing use of immune-based therapies, including the widely used class of agents known as immune checkpoint inhibitors, has exposed a discrete group of immune-related adverse ...
Abdallah, K.+80 more
core +2 more sources
ABSTRACT Maribavir's anti‐cytomegalovirus (CMV) activity and favorable safety/tolerability profile is a welcomed addition to the CMV treatment armamentarium. To further characterize pharmacokinetic (PK) and exposure–response relationships of maribavir in transplant recipients with CMV, a population PK model was updated with data from the AURORA study ...
Kefeng Sun+6 more
wiley +1 more source
View Point on Severe Fever with Thrombocytopenia Syndrome
Abstract Severe fever with thrombocytopenia syndrome (SFTS), a new disease of zoonotic natural foci has been increasing in recent years. In this review, the disease of human granulocytic anaplasmosis infection due to tickborne and new Bunia virus infection, have similar clinical symptoms. Total of 11 articles were retrieved.
Tai-Sheng Li+3 more
openaire +2 more sources
Emerging tick-borne infections in mainland China: an increasing public health threat [PDF]
Since the beginning of the 1980s, 33 emerging tick-borne agents have been identified in mainland China, including eight species of spotted fever group rickettsiae, seven species in the family Anaplasmataceae, six genospecies in the complex Borrelia ...
Cao, Wu-Chun+17 more
core +1 more source