Results 161 to 170 of about 54,939 (306)
COVID19‐Related Onset and Relapses of Juvenile Systemic Lupus Erythematosus‐Like Disease
Journal of Paediatrics and Child Health, EarlyView.
Chiara Cannata+3 more
wiley +1 more source
FIGO guideline on liver disease and pregnancy
Abstract The number of women entering pregnancy with chronic liver disease is rising. Gestational liver disorders affect 3% of the pregnant population. Both can be associated with significant maternal and fetal morbidity and mortality. European guidance has recently been published to inform management.
Melanie Nana+24 more
wiley +1 more source
Pathogenesis of emerging severe fever with thrombocytopenia syndrome virus in C57/BL6 mouse model
Cong Jin+23 more
openalex +1 more source
ABSTRACT Introduction Hemophagocytic lymphohistiocytosis (HLH) is characterized by macrophage and cytotoxic lymphocyte hyperactivation, fever, pancytopenia, liver dysfunction, and abnormal coagulation. However, no specific treatments have been established for HLH caused by immune checkpoint inhibitors.
Tomoko Honda+9 more
wiley +1 more source
Cytokine and Chemokine Levels in Patients with Severe Fever with Thrombocytopenia Syndrome Virus
Baocheng Deng+17 more
openalex +2 more sources
Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley +1 more source
ABSTRACT Human adenoviruses of species B (HAdV‐B) can cause upper respiratory tract infections and conjunctivitis, but also severe lower respiratory tract infections (LRTI). Although HAdV‐associated LRTI are non‐notifiable in Germany, typing data of our Adenovirus Reference Laboratory indicated an HAdV‐B3 epidemic in 2023, with 67 samples initially ...
Tina Ganzenmueller+5 more
wiley +1 more source
Two confirmed cases of severe fever with thrombocytopenia syndrome with pneumonia: implication for a family cluster in East China [PDF]
Yiyi Zhu+8 more
openalex +1 more source
Phase I Clinical Trial of CVL218, a Novel PARP1/2 Inhibitor, in Patients with Advanced Solid Tumors
CVL218, a PARP1/2 inhibitor, was generally well tolerated and safe in solid tumors. It showed potential antitumor activity in patients treated with the recommended dose (700 mg BID). ABSTRACT CVL218, a novel poly ADP‐ribose polymerase (PARP1/2) inhibitor, has strong PARP1/2 selective inhibitory activity and high oral bioavailability. We aimed to assess
Zihong Chen+12 more
wiley +1 more source