Results 181 to 190 of about 54,939 (306)

Patients With IgA Vasculitis and Kawasaki Disease Show Dysregulated Interferon Signature

International Journal of Rheumatic Diseases, Volume 28, Issue 7, July 2025.
ABSTRACT Objective IgA vasculitis (IgAV) and Kawasaki disease (KD) are the most common forms of childhood vasculitis. Although various factors such as viral infections, genetic factors, and environmental factors are involved in the development of both diseases, their pathogenesis remains unclear.
Sevki Erdem Varol, Cisem Cinar, Nihan Burtecene, Sezgin Sahin, Mehmet Yildiz, Kenan Barut, Haluk Cokugras, Sinem Firtina, Ozgur Kasapcopur, Ayca Kiykim   +9 more
wiley   +1 more source

Genetic Susceptibility Is One of the Determinants for Severe Fever with Thrombocytopenia Syndrome Virus Infection and Fatal Outcome: An Epidemiological Investigation

, 2015
Jimin Sun, Yuming Tang, Ling Feng, Yue Chang, Xiaohong Ye, Wen Shi, Lei Zhang, Zhiping Chen, Haijiang Lin, Zaiping Qiu, Yanjun Zhang, Rong Zhang, Haiyan Mao, Enfu Chen, Junfen Lin, Jianmin Jiang, Shichang Xia, Zhenyu Gong   +17 more
openalex   +2 more sources

Analysis of clinical features and early warning indicators of death from severe fever with thrombocytopenia syndrome [PDF]

, 2018
Xiaowen Xu, Zhenlu Sun, Jingyu Liu, Jianjun Zhang, Tao Liu, Xiaodong Mu, Mei Jiang   +6 more
openalex   +1 more source

Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of HSK39297 in Chinese Healthy Subjects: A Phase 1 Clinical Trial

Clinical and Translational Science, Volume 18, Issue 7, July 2025.
ABSTRACT HSK39297 is a novel complement factor B inhibitor, and this phase 1 trial was designed to assess its pharmacokinetics (PK), pharmacodynamics (PD), safety, and tolerability in healthy Chinese subjects. This study included 46 subjects in the single ascending dose (SAD) part (50–600 mg) and 50 subjects in the multiple ascending dose (MAD) part ...
Yuyang Dai, Feng Wu, Siyang Ni, Xiaojun Hu, Ying Han, Ying Jiao, Huan Lu, Yilin Liu, Lingling Wang, Yunfei Lin, Meixia Chen, Chao Wang, Qinghe Wu, Fangqiong Li, Laichun Lu   +14 more
wiley   +1 more source

Activated partial thromboplastin time predicts mortality in patients with severe fever with thrombocytopenia syndrome: A multicenter study in north China

Heliyon
Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease with high lethality. This study aimed to determine whether prolonged activated partial thromboplastin time (APTT) predicted SFTS mortality.
Wenjuan Peng, Junnan Li, Hong Yu, Wei Zhou, Ling Lin, Ziruo Ge, Jianming Lai, Zhihai Chen, Liuluan Zhu, Zhenghua Zhao, Yi Shen, Ronghua Jin, Jianping Duan, Wei Zhang   +13 more
doaj  

Fatal Severe Fever with Thrombocytopenia Syndrome: An Autopsy Case Report

, 2016
Natsumi Uehara, Takao Yano, Akira Ishihara, Masayuki Saijou, Tadaki Suzuki   +4 more
openalex   +1 more source

Extensive severe fever with thrombocytopenia syndrome virus contamination in surrounding environment in patient rooms [PDF]

, 2018
Byung-Han Ryu, Jin Yong Kim, T. Kim, M.-C. Kim, M.J. Kim, Yong Pil Chong, S.-O. Lee, Sang‐Ho Choi, Y.S. Kim, Jun Hee Woo, Sung‐Han Kim   +10 more
openalex   +1 more source

Influence of Genetic Variation of GST, CYP, and ABC on the Safety and Efficacy of Cyclophosphamide‐Based Therapy

Clinical and Translational Science, Volume 18, Issue 7, July 2025.
ABSTRACT Cyclophosphamide (CTX) is one of the most widely used drugs in the clinical treatment of tumors and autoimmune diseases. The correlation between CYP, GST, and ABC gene polymorphisms and CTX activity and its induced toxicity has been extensively studied, but with inconsistent conclusions.
Zhong‐Wei Yao, Qi‐Long Li, Wei‐Feng Hu, Ling‐Hui Pan, Jun‐Wen Wu, Wen‐Lu Ren, Hui‐Tian Jia, Pan‐Pan Wang, Zhi‐Ying Fu, He Zhu   +9 more
wiley   +1 more source

Avoiding early diagnosis

Journal of General and Family Medicine, Volume 26, Issue 4, Page 292-296, July 2025.
Takao Wakabayashi, Goh Keng Wee, Mikinosuke Ishibashi, Yoshiki Akiyama, Naoki Kanda, Tomoyuki Watanabe   +5 more
wiley   +1 more source

Continuous Renal Replacement Therapy: Application of Kidney Disease Improving Global Outcomes Guidelines for Treatment Prescription in Dogs With Acute Kidney Injury and Outcome Prediction

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background Continuous renal replacement therapy (CRRT) is routinely used in human patients with acute kidney injury (AKI) but studies in dogs are scarce. Objective To describe CRRT in dogs and assess the utility of a previously validated scoring system for dogs with AKI undergoing hemodialysis, and the Acute Patient Physiological and ...
Hilli Raskansky, Yaron Bruchim, Ran Nivy
wiley   +1 more source