Results 211 to 220 of about 65,145,522 (276)

Dengue Virus Molecular Targets and Antiviral Drug Development: Advances, Challenges and Therapeutic Perspectives

open access: yesChemistrySelect, Volume 11, Issue 33, 1 September 2026.
This narrative review analyzes DENV molecular targets, including structural proteins (C, prM/M, E), non‐structural components (NS1NS5), and host factors, alongside small‐molecule candidates in preclinical and clinical phases. Owing to high structural conservation, the NS2B‐NS3 protease and NS5 (RdRp/MTase) remain primary drug discovery focuses, while ...
Aryane Lucia da Silva Aguiar De Oliveira   +8 more
wiley   +1 more source

Safety Signals of CRS and ICANS With Tarlatamab in Relapsed Small Cell Lung Cancer: Insights From a Small Case Study

open access: yesThoracic Cancer, Volume 17, Issue 18, September 2026.
In 11 patients with relapsed small cell lung cancer treated with tarlatamab, CRS occurred in 63.6% and was limited to cycle 1 day 1 or day 8; all events were Grade 1–2 and manageable without tocilizumab or treatment discontinuation. One patient developed Grade 3 ICANS and fully recovered, while NLR showed an exploratory association with CRS.
Juwhan Choi, Seunghun Lee, Sung Yong Lee
wiley   +1 more source

Home telemonitoring in high‐risk pregnancies: A Finnish retrospective cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 9, Page 1689-1697, September 2026.
This retrospective study suggests that home telemonitoring may provide an acceptable approach for managing selected high‐risk pregnancies. Safe and effective implementation requires careful patient selection and adherence to evidence‐based clinical protocols.
Tiina Stark, Heidi Kruit, Leena Rahkonen
wiley   +1 more source

Transmission of severe fever with thrombocytopenia syndrome virus from a dog to humans and a cat in a household cluster. [PDF]

open access: yesOne Health
Ma D   +11 more
europepmc   +1 more source

Postoperative Care and Management in Pediatric Hematology‐Oncology Patients

open access: yesEuropean Journal of Haematology, Volume 117, Issue 3, Page 673-681, September 2026.
ABSTRACT Pediatric patients with hematologic and oncologic diseases often undergo surgical procedures as part of diagnosis and therapy. These include central venous catheter placements, tumor resections, lymph node and bone marrow biopsies, among others.
Shachi Srivatsa, Sara A. Mansfield
wiley   +1 more source

When to consider an inborn error of immunity: clues for physicians

open access: yesInternal Medicine Journal, Volume 56, Issue 9, Page 1488-1499, September 2026.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

Home - About - Disclaimer - Privacy