Animal Model of Severe Fever With Thrombocytopenia Syndrome Virus Infection [PDF]
Severe fever with thrombocytopenia syndrome (SFTS), an emerging life-threatening infectious disease caused by SFTS bunyavirus (SFTSV; genus Bandavirus, family Phenuiviridae, order Bunyavirales), has been a significant medical problem.
Jiawen Sun +12 more
doaj +3 more sources
A role for glycolipid biosynthesis in severe fever with thrombocytopenia syndrome virus entry [PDF]
A novel bunyavirus was recently found to cause severe febrile illness with high mortality in agricultural regions of China, Japan, and South Korea. This virus, named severe fever with thrombocytopenia syndrome virus (SFTSV), represents a new group within the Phlebovirus genus of the Bunyaviridae.
Mary Jane Drake +8 more
openaire +6 more sources
Severe Fever with Thrombocytopenia Syndrome, South Korea, 2012 [PDF]
We report a retrospectively identified fatal case of severe fever with thrombocytopenia syndrome (SFTS) in South Korea from 2012. SFTS virus was isolated from the stored blood of the patient.
Kye-Hyung Kim +9 more
doaj +2 more sources
Comprehensive Surveillance of Severe Fever with Thrombocytopenia Syndrome Virus in Patients with Acute Febrile Illness, Wild Rodents, and Trombiculid Larval Mites, Thailand [PDF]
Infection with severe fever with thrombocytopenia syndrome (Bandavirus dabieense) virus poses a substantial public health threat because of its high mortality rates and severe complications.
Piyada Linsuwanon +11 more
doaj +2 more sources
Experimental infections of mosquitoes with severe fever with thrombocytopenia syndrome virus [PDF]
Background Severe fever with thrombocytopenia syndrome (SFTS) is a newly identified emerging infectious disease, which is caused by a novel bunyavirus (termed SFTSV) in Asia.
Shu-Yi Liang +9 more
doaj +3 more sources
Evolutionary and molecular analysis of the emergent severe fever with thrombocytopenia syndrome virus [PDF]
In 2009, a novel Bunyavirus, called severe fever with thrombocytopenia syndrome virus (SFTSV) was identified in the vicinity of Huaiyangshan, China. Clinical symptoms of this zoonotic virus included severe fever, thrombocytopenia, and leukocytopenia, with a mortality rate of ~10%.
Lam, TTY +8 more
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Severe fever with thrombocytopenia syndrome virus expands its borders
The outbreak of avian-origin influenza A (H7N9) virus in eastern China1,2 has reminded the world of the imminent threat of unexpected pathogens, including an “old” virus, influenza.
Ying Wu, George F Gao
doaj +3 more sources
Recent Advances in Therapeutics for Severe Fever with Thrombocytopenia Syndrome Virus. [PDF]
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne bunyavirus with a mortality rate of up to 30%. There is no specific treatment for SFTSV. This article systematically reviews the progress of major anti-SFTSV drugs. The nucleotide analogues (favipiravir, 4′-fluorouridine diphosphate prodrug VV261) have shown clinical potential ...
Dang H +5 more
europepmc +3 more sources
The Emergence of Severe Fever with Thrombocytopenia Syndrome Virus [PDF]
Severe fever with thrombocytopenia syndrome (SFTS) is a newly recognized hemorrhagic fever disease found throughout Asia with a case fatality rate between 12% and 30%. Since 2009, SFTS has been reported in China throughout 14 Chinese Provinces. In addition, SFTS has been recognized in South Korea and Japan with the first confirmed cases reported in ...
Jesus A, Silvas, Patricia V, Aguilar
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Entry of severe fever with thrombocytopenia syndrome virus [PDF]
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a globe-shaped virus covered by a dense icosahedral array of glycoproteins Gn/Gc that mediate the attachment of the virus to host cells and the fusion of viral and cellular membranes. Several membrane factors are involved in virus entry, including C-type lectins and nonmuscle myosin heavy ...
Fei, Yuan, Aihua, Zheng
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