Results 171 to 180 of about 2,972,520 (248)

Fifty Shades of Calpain: Couplon Breakdown in Catecholaminergic Polymorphic Ventricular Tachycardia and Beyond. [PDF]

Circ Res
Do TQ, Knollmann BC.
europepmc   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source

Global Burden of Upper Airway Infections: Epidemiology, Current Challenges and Future Perspectives. [PDF]

Infect Dis Rep
Guarino P, Chiari F, La Via L, Marino A, Lechien JR, Lentini M, Lavalle S, Nunnari G, Maira S, Botto CG, Ferlito S, Maniaci A.   +11 more
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Pulmonary artery dissection with patent ductus arteriosus presenting with differential cyanosis: a case report and review of literature. [PDF]

Front Cardiovasc Med
Liu Y, Yuan D.
europepmc   +1 more source

Hot and cold deserts as eco‐evolutionary arenas for understanding plant resistance to multiple abiotic stressors

Biological Reviews, EarlyView.
ABSTRACT During their long evolutionary history, land plants have evolved a range of adaptations to different abiotic stressors. These help explain present‐day diversity and distribution patterns, as well as the potential resilience of natural and agricultural systems to a changing climate. Most previous research has focused on adaptation to individual
Marc Fradera‐Soler, Natasha Barbolini, Anže Žerdoner Čalasan, Marian Schubert, Catarina Rydin, Olwen M. Grace, Aelys M. Humphreys   +6 more
wiley   +1 more source

Hepatic Mycotic Aneurysms in TAVI-Associated Infective Endocarditis Caused by <i>Streptococcus gallolyticus</i>: A Case Report. [PDF]

Reports (MDPI)
Grigore M, Nicolae C, Moldovan H, Balahura AM, Ilieșiu AM.   +4 more
europepmc   +1 more source

The Degradation of Access‐Based Business Models: Customer Misbehavior and Shared Mobility

Business Strategy and the Environment, EarlyView.
ABSTRACT Access‐based services are considered one of the strategies to embed sustainability in business models. Yet, because the evolution of these business models has been overlooked, we do not know whether their promise to create triple value is sustained.
Andres Camacho, Carmen Valor
wiley   +1 more source

How to Navigate Disrupted Business Models in the 21st Century: At the Crossroads of the Circular Economy and the Industry 4.0 Transition

Business Strategy and the Environment, EarlyView.
ABSTRACT Our planet faces a critical crisis, with pollution, resource depletion and biodiversity loss surpassing sustainable limits. Businesses must address these challenges, with the circular economy and Industry 4.0 offering transformative potential through closed‐loop systems, regenerative solutions and advanced technologies.
Agnes Toth‐Peter, Rui Torres de Oliveira, Shane Mathews, Leonie Barner   +3 more
wiley   +1 more source