Results 161 to 170 of about 628,141 (359)
Advanced Science, EarlyView.Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing +4 more
wiley +1 more source
Obesity of Mentally Retarded Individuals: Prevalence, Characteristics, and Intervention [PDF]
, 1985 Research on the prevalence, characteristics, and treatment of obesity of mentally retarded individuals within the context of research findings with the obese nonretarded population was selectively reviewed.
Burkhart, Jennifer E. +2 more
core +1 more source
Advanced Science, EarlyView.This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv +8 more
wiley +1 more source
Advanced Science, EarlyView.Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim +9 more
wiley +1 more source
The Application of Clinical Genetics, 2019 Ihuoma Eneli,1,2 Jinyu Xu,1 Matthew Webster,3 Amy McCagg,3 Lex Van Der Ploeg,3 Alastair S Garfield,3 Elizabeth Estrada41Center for Healthy Weight and Nutrition, Nationwide Children’s Hospital, Columbus, OH, USA; 2Department of Pediatrics, The Ohio ...
Eneli I +6 more
doaj
Gastric emptying in normal weight, obese and severely obese children
, 1998 Marisa Chiloiro +4 more
openalex +1 more source
The Impact of Bariatric Surgery on Severely Obese Patients With Diabetes [PDF]
, 2003 Daniel Eisenberg, Robert L. Bell
openalex +1 more source
Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling
Advanced Science, EarlyView.The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen +13 more
wiley +1 more source
Autosomal-Dominant Mode of Inheritance of a Melanocortin-4 Receptor Mutation in a Patient with Severe Early-Onset Obesity Is Due to a Dominant-Negative Effect Caused by Receptor Dimerization [PDF]
, 2003 Heike Biebermann +5 more
openalex +1 more source
Advanced Science, EarlyView.Cartilage injury is a prominent pathological hallmark of osteoarthritis. In this study, we developed a two‐modular hydrogel microparticle system wherein HMP‐A effectively targets the damaged area, while HMP‐B forms an efficient connection with HMP‐A on the cartilage surface.
Xinye Chen +5 more
wiley +1 more source