Results 171 to 180 of about 4,253,715 (400)

Symptoms of anxiety and depression and health-related quality of life in women with severe obesity and polycystic ovary syndrome and the effect of a one year weight loss intervention [PDF]

, 2023
Josefin Kataoka, Marie Olsson, Eva Lindgren, Ingrid Larsson, Johanna Schmidt, Anna Benrick, Elisabet Stener‐Victorin   +6 more
openalex   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

The Impact of Class III Obesity on Outcomes for Vestibular Schwannoma Surgery: A Case Report

Diagnostics
Background and Clinical Significance: Vestibular schwannomas (VS) are benign tumors arising from Schwann cells of the eighth cranial nerve. They represent approximately 8% of all intracranial tumors and have an increasing incidence.
Tomaž Šmigoc, Hojka Rowbottom, Janez Ravnik   +2 more
doaj   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Micronutrient status 2 years after bariatric surgery: a prospective nutritional assessment

Frontiers in Nutrition
BackgroundAmong commonly performed bariatric surgeries, biliopancreatic diversion with duodenal switch (BPD-DS) provides greater weight loss than Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG), with sustained metabolic improvements.
Marianne Côté, Marianne Côté, Laurence Pelletier, Laurence Pelletier, Mélanie Nadeau, Léonie Bouvet-Bouchard, Léonie Bouvet-Bouchard, François Julien, François Julien, Andréanne Michaud, Andréanne Michaud, Laurent Biertho, Laurent Biertho, André Tchernof, André Tchernof   +14 more
doaj   +1 more source

Seipin‐Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu, Junxia Zhang, Yusi Chen, Geng Shen, Yufei Han, Zihao Zhou, Jinxuan Chen, Xuya Kang, Huilin Qu, Jiaxin Duanmu, Haibao Shang, Yingjia Li, Wei Huang, Yan Zhang   +13 more
wiley   +1 more source

Hyperglycemia and Obesity as Risk Factors for Severe Covid-19 [PDF]

, 2023
Komang Ida Widiayu Radiari Nugraha, Ida Bagus Ngurah, I Gede Ketut Sajinadiyasa, Wira Gotera, Ni Wayan Candrawati, Ida Ayu Jasminarti Dwi Kusumawardani, Ni Luh Putu Eka Arisanti, I Gusti Ngurah Bagus Artana   +7 more
openalex   +1 more source

Trends in Obesity and Severe Obesity Prevalence in US Youth and Adults by Sex and Age, 2007-2008 to 2015-2016

Journal of the American Medical Association (JAMA), 2018
Craig M. Hales, C. Fryar, M. Carroll, D. Freedman, Cynthia L Ogden   +4 more
semanticscholar   +1 more source

PLA2G16‐Mediated Tetracosatetraenoic Acid Rewires Fatty Acid Oxidation to Impair CD8+ T Cell Immune Function in Promoting Breast Cancer Lung Metastasis

Advanced Science, EarlyView.
Illustrating how tumor‐derived PLA2G16 regulates tetracosatetraenoic acid (C24:4 (n‐6)) accumulation and CD8+ T cell activation via the C24:4‐PPARα‐FAO axis in early metastatic niches, thereby promoting lung metastasis of triple‐negative breast cancer.
Yubi Gan, Die Meng, Lei Lang, Jing Luo, Peijin Dai, Chao Chang, Zexiu Lu, Yuetong Guo, Rui Wang, Shanchun Chen, Xi Tang, Yixuan Hou, Dongmei Tan, Manran Liu   +13 more
wiley   +1 more source

QuickStats: Prevalence of Obesity* and Severe Obesity^† Among Persons Aged 2–19 Years — National Health and Nutrition Examination Survey, 1999–2000 through 2017–2018 [PDF]

, 2020

openalex   +1 more source