Results 231 to 240 of about 4,253,715 (400)

Patients With Obesity-Related Hypertension Treated With Renin-Angiotensin-Aldosterone System Antagonists Exhibit Lower Mortality And Less Severe COVID-19: A Retrospective Study

open access: gold, 2021
Vijayvardhan Kamalumpundi   +6 more
openalex   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

open access: yesAdvanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia   +11 more
wiley   +1 more source

PREVALENCE OF MODERATE OR SEVERE LEFT VENTRICULAR DIASTOLIC DYSFUNCTION IN OBESE PERSONS WITH OBSTRUCTIVE SLEEP APNEA [PDF]

open access: bronze, 2005
Jasdeep Sidana   +6 more
openalex   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

Outcomes of Liver Transplantation in Patients With Severe Obesity: The Impact of Performance Status. [PDF]

open access: yesTransplant Direct
Cracco A   +8 more
europepmc   +1 more source

Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex

open access: green, 2009
Michelle A. King   +15 more
openalex   +1 more source

Evaluating the Association of <i>FAAH</i> Common Gene Variation with Childhood, Adult Severe Obesity and Type 2 Diabetes in the French Population [PDF]

open access: bronze, 2008
Emmanuelle Durand   +10 more
openalex   +1 more source

Elastic Power of Mechanical Ventilation in Morbid Obesity and Severe Hypoxemia [PDF]

open access: bronze, 2020
Muhammad K. Hayat Syed   +4 more
openalex   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

open access: yesAdvanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie   +8 more
wiley   +1 more source

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