Results 311 to 320 of about 4,253,715 (400)

Nanoparticle‐Based Tolerogenic Vaccines: Next‐Generation Strategies for Autoimmune and Allergic Disease Therapies

Angewandte Chemie, EarlyView.
Nanoparticle‐based tolerogenic vaccines harness controlled antigen delivery and immunomodulation to establish tolerance in autoimmunity and allergy. This review outlines how nanoparticle design (size, shape, composition, administration route) influences biodistribution and immune‐cell targeting.
Benjamin E. Nachod, Ajay S. Thatte, Rohan Palanki, Michael J. Mitchell   +3 more
wiley   +2 more sources

Free Fatty Acids and Complex Lipids in Patients With Severe Obesity Treated With Roux-En-Y Gastric Bypass: Impact of Diabetes Status. [PDF]

Biochem Res Int
Eriksen F, Madsbad S, Fenger M, Carlsson ER.   +3 more
europepmc   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Association of Chrono-Nutritional Profiles with Weight Loss and Comorbidity Remission After Bariatric Surgery in Patients with Severe Obesity. [PDF]

Nutrients
Bettini S, Carraro E, Pilatone A, Schiff S, Girardi P, D'Angelo M, Begolli A, Mansouri F, Toosinezhad S, Sandri S, Gusella B, Milan G, Foletto M, Fioretto P, Busetto L.   +14 more
europepmc   +1 more source

Electronic Health Records to Test Multimorbidity Influences to Plasma Biomarker Interpretation for Alzheimer's Disease

Annals of Neurology, EarlyView.
Objective Plasma biomarkers of Alzheimer's disease (AD) pathology are frequently tested in specialized research settings, which limits the generalizability of findings. Using electronic health records and banked plasma, we evaluated plasma biomarkers—phosphorylated tau 217 (p‐tau217), β‐amyloid 1–42/1–40 (Aβ42/Aβ40) and p‐tau217/Aβ42—in a real‐world ...
Katheryn A.Q. Cousins, Rory Boyle, Colleen Morse, Anurag Verma, Christopher A. Brown, Kyra S. O'Brien, Marina Serper, Nadia Dehghani, Penn Medicine BioBank, Corey T. McMillan, Edward B. Lee, Leslie M. Shaw, David A. Wolk   +12 more
wiley   +1 more source

Applicability of multiple quantitative ultrasound liver biomarkers in children and adolescents with severe obesity. [PDF]

BMC Pediatr
Cetinic I, de Lange C, Lagerstrand K, Kindblom JM, Sjögren L, Hebelka H.   +5 more
europepmc   +1 more source

Cross-cultural validation and Spanish translation of the Boston Interview to evaluate severely obese patients seeking metabolic/bariatric surgery

Míriam Esther Pelayo Delgado, Stephanie Sogg, DeAnna L. Mori, Teresa Rodríguez Cano, Luis Beato‐Fernández, Rocío Campos del Portillo, Ana Royuela Vicente, Juan José de Frutos Guijarro, M. García-Oria, Mariano Artés Caselles, Irene Bretón Lesmes, Elena Carrillo Lozano, Ana Sánchez Ramos, Irene Baños Martín, Iosune Torio Palmero, Antonio Alcantara Tadeo, María Teresa González Salvador, Maria Rosario de Arce Cordón, Enrique Baca‐García   +18 more
openalex   +1 more source

Prevalence of Extremely Severe Obesity and Metabolic Dysfunction Among US Children and Adolescents.

JAMA Netw Open
Münte E, Zhang X, Khurana A, Hartmann P.   +3 more
europepmc   +1 more source

Barriers and facilitators to the initiation and maintenance of exercise training for women with clinically severe obesity before, during and after participation in a weight loss study: a qualitative investigation. [PDF]

BMJ Open Sport Exerc Med
van den Hoek D, Miller C, Fraser S, Sudholz B, Selig S, Dixon J, Teychenne M.   +6 more
europepmc   +1 more source

Genomic deletions on 16p11.2 associated with severe obesity in Brazil. [PDF]

Front Endocrinol (Lausanne)
da Silva Assis IS, Salum KCR, Felício RFM, Palhinha L, de Medeiros Abreu G, Silva T, Mattos FCC, Rosado EL, Zembrzuski VM, Campos Junior M, Maya-Monteiro CM, Cabello PH, Carneiro JRI, Bozza PT, da Fonseca ACP.   +14 more
europepmc   +1 more source