Results 71 to 80 of about 4,253,715 (400)

Psychological symptoms in obesity and related factors [PDF]

, 2015
Introduction: This study aimed to investigate the relationship between levels of depression and anxiety symptoms and quality of life, self-esteem in obesity.
Değirmenci, T., Fenkçi, S., Kalkan Oğuzhanoğlu, Nazan, Sözeri-Varma, G., Özdel, O.   +4 more
core   +1 more source

Genetic architecture of human thinness compared to severe obesity

PLoS Genetics, 2019
The variation in weight within a shared environment is largely attributable to genetic factors. Whilst many genes/loci confer susceptibility to obesity, little is known about the genetic architecture of healthy thinness.
R. F., Mistry V, Bounds R, Hendricks A, Keogh Jm, T. H, Henning E, Corbin Lj, Society Scientific Group Understanding, O'Rahilly S, Zeggini E, Wheeler E, Barroso I, Farooqi Is   +13 more
semanticscholar   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

A Rare Potential Pathogenic Variant in the BDNF Gene is Found in a Brazilian Patient with Severe Childhood-Onset Obesity

Diabetes, Metabolic Syndrome and Obesity, 2021
Ana Carolina Proença da Fonseca,1,2 Gabriella de Medeiros Abreu,2 Lohanna Palhinha,1 Verônica Marques Zembrzuski,2 Mario Campos Junior,2 João Regis Ivar Carneiro,3 José Firmino Nogueira Neto,4 Fernanda Cristina C Mattos Magno,5
da Fonseca ACP, Abreu GM, Palhinha L, Zembrzuski VM, Campos Junior M, Carneiro JRI, Nogueira Neto JF, Magno FCCM, Rosado EL, Maya-Monteiro CM, Cabello GMK, Cabello PH, Bozza PT   +12 more
doaj  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Trends and Subgroup Comparisons of Obesity and Severe Obesity Prevalence Among Mississippi Adults, 2011–2021

Obesities
Mississippi has long been one of the most obese states in the U.S., with its obesity rates consistently exceeding the national average. The state’s severe obesity rate is also among the highest in the nation.
Stephanie McLeod, Xiaoshan Z. Gordy, Jana Bagwell, Christina Ferrell, Jerome Kolbo, Lei Zhang   +5 more
doaj   +1 more source

The Bidirectional Relationship Between Obstructive Sleep Apnea and Metabolic Disease [PDF]

, 2018
Obstructive sleep apnea (OSA) is a common sleep disorder, effecting 17% of the total population and 40–70% of the obese population (1, 2). Multiple studies have identified OSA as a critical risk factor for the development of obesity, diabetes, and ...
Arble, Deanna M., Framnes, Sarah N.
core   +3 more sources

Major microbiota dysbiosis in severe obesity: fate after bariatric surgery

Gut, 2018
Objectives Decreased gut microbial gene richness (MGR) and compositional changes are associated with adverse metabolism in overweight or moderate obesity, but lack characterisation in severe obesity.
J. Aron‐Wisnewsky, Edi Prifti, Eugeni Belda, F. Ichou, B. Kayser, M. Dao, E. Verger, L. Hedjazi, J. Bouillot, J. Chevallier, N. Pons, E. Le Chatelier, F. Levenez, S. Ehrlich, J. Dore, Jean-Daniel Zucker, K. Clément   +16 more
semanticscholar   +1 more source

Association of Metabolic Surgery With Major Adverse Cardiovascular Outcomes in Patients With Previous Myocardial Infarction and Severe Obesity: A Nationwide Cohort Study.

Circulation, 2020
BACKGROUND: The number of patients with myocardial infarction and severe obesity is increasing and there is a lack of evidence how these patients should be treated.
E. Näslund, E. Stenberg, R. Hofmann, J. Ottosson, M. Sundbom, R. Marsk, P. Svensson, K. Szummer, T. Jernberg   +8 more
semanticscholar   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source