The Preparation of Novel Fluorenes Inspired by Hipposudoric Acid
In this research we report on the design and synthesis of a series of fluorene‐based derivatives loosely inspired by the tricyclic framework of hipposudoric acid. Preparation of sixteen novel N‐alkylated derivatives was accomplished via a series of concise one‐step amide N‐alkylation reactions.
Munib Uddin +3 more
wiley +1 more source
Activated immune cells present a lung interstitial-to-airway/alveolar cross-compartment sharing pattern in severe pneumonia. [PDF]
Zhao Y +8 more
europepmc +1 more source
ABSTRACT This study explores incidental learning among physicians navigating uncertainty during the COVID‐19 pandemic. Using a constructivist research design, we conducted a literature review of 13 empirical studies on incidental learning in complexity and analyzed critical incident interviews with 12 emergency medicine and intensive care physicians ...
Henriette Lundgren +4 more
wiley +1 more source
Development and Validation of a Nomogram Model to Predict the Risk of Severe Pneumonia in Children with Pneumococcal Infection. [PDF]
Li D +8 more
europepmc +1 more source
ABSTRACT Complication reporting in spinal tumor surgery remains inconsistently defined. We aimed to quantify the incidence, severity, and spectrum of early (≤ 30 days) postoperative adverse events (AEs) in spinal tumor surgery and to identify predictors of overall and serious complications using standardized severity grading.
Meltem Ivren +6 more
wiley +1 more source
Unveiling metagenomic and metabolomic signatures in mild and severe pneumonia caused by <i>Mycoplasma pneumoniae</i> in children. [PDF]
Yang Y +9 more
europepmc +1 more source
Abstract Autoimmune encephalitis is a group of disorders characterized by symptoms of dysfunction of the limbic and extra‐limbic systems that occur in association with antibodies against intracellular antigens, synapses, or proteins located on the surface of nerve cells. Anti‐NMDA (N‐methyl‐D‐aspartate) receptor encephalitis was first described in 2007
Pham Ba Nha +6 more
wiley +1 more source
Serum levels of PTEN and progranulin as potential diagnostic and prognostic biomarkers for severe pneumonia in the elderly. [PDF]
Ge Y, Lu W, Liu J, Liang H, Xu L.
europepmc +1 more source
Optimal timing for induction of labor in normotensive women: A retrospective cohort study
Abstract Objective Labor induction is offered to reduce the risk of stillbirth at late term (41+0 to 41+6) but earlier induction in normotensive singleton pregnancies is supported by weak evidence. The aim of the present study was to investigate the optimal timing for induction in normotensive women.
Jóhanna Gunnarsdóttir +3 more
wiley +1 more source
Interpretable machine learning identifies immune-inflammatory and immunothrombotic biomarkers for myocardial injury and mortality risk stratification in severe pneumonia with diverse infectious etiologies. [PDF]
Wang Y +9 more
europepmc +1 more source

