Results 51 to 60 of about 2,103,669 (285)

Severe Community-Acquired Pneumonia [PDF]

open access: yesAnaesthesia and Intensive Care, 1997
Severe community-acquired pneumonia is now considered a separate clinical entity that is important to recognize, particularly because of its high mortality rate. This article reviews several of the studies published in the past year that focus on risk and prognostic factors, etiology, diagnostic evaluation, pathogenesis, and therapy of this important ...
openaire   +4 more sources

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin   +11 more
wiley   +1 more source

Association of modifiable risk factors with severity of pneumonia in children aged 2 months to 5 years: a prospective cross-sectional study from a tertiary care hospital in Mumbai

open access: yesEgyptian Pediatric Association Gazette
Background Pneumonia is a leading cause of morbidity and mortality in children under five years, especially in developing countries. Although the risk factors for childhood pneumonia are well documented, the relative contribution of these factors to ...
Sushma Save, Ashwini Patil, Unmesh Dev
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Systemic bacteraemia in children presenting with clinical pneumonia and the impact of non-typhoid salmonella (NTS)

open access: yesBMC Infectious Diseases, 2010
Background The diagnosis and antimicrobial treatment of pneumonia in African children in the absence of diagnostic means such as x-ray facilities or microbiological laboratories relies primarily on clinical symptoms presented by the patients. In order to
Dekker Denise   +14 more
doaj   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky   +5 more
wiley   +1 more source

Statins Reduce Mortality After Non-severe but Not After Severe Pneumonia: A Systematic Review and Meta-Analysis

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2015
PURPOSE: The objective of this study was to perform a systematic review and meta-analysis of the effects of statins on mortality for patients with non-severe pneumonia or severe pneumonia. METHODS: PubMed, EMBASE, Cochrane Database of Systematic Reviews,
Mingwang Jia   +4 more
doaj   +1 more source

Hospital management of community-acquired pneumonia in Malta [PDF]

open access: yes, 2012
Community-acquired pneumonia (CAP) remains a common diagnosis requiring hospital admission and a leading cause of death worldwide. No local guideline is currently available for the management of CAP.
Mamo, Jonathan   +3 more
core  

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

Recommendations for diagnosing and treating severe Mycoplasma pneumoniae pneumonia in children: clinical practice protocols from the Third Affiliated Hospital of Sun Yat-sen University [PDF]

open access: yesXin yixue
Mycoplasma pneumoniae pneumonia (MPP) is a common cause of community-acquired pneumonia in children aged 5 and older in China. Although most affected children have favorable clinical prognosis, some cases can escalate into severe MPP due to risk factors ...
YANG Kexin, PAN Li, ZENG Jinqing, LI Zhongke, LI Xufeng, ZHU Lingping, LIANG Ying, YANG Lifen, ZHANG Kun, DAI Min, CHEN Zhuanggui, LI Yating
doaj   +1 more source

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