Results 111 to 120 of about 3,781,222 (303)

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Continuous Professional Oral Health Care Intervention Improves Severe Aspiration Pneumonia

Case Reports in Dentistry, 2019
Professional oral health care (POHC) is known to prevent aspiration pneumonia in patients with dysphagia and/or those at the perioperative stage of surgery. However, the effect of POHC on patients suffering from aspiration pneumonia remains unknown. Here,
Wakako Nawata, Yojiro Umezaki, Masahiro Yamaguchi, Masato Nakajima, Michiko Makino, Masahiro Yoneda, Takao Hirofuji, Takafumi Yamano, Hiroaki Ooboshi, Hiromitsu Morita   +9 more
doaj   +1 more source

Clinical Characteristics of Patients with Severe Pneumonia Caused by the 2019 Novel Coronavirus in Wuhan, China

medRxiv, 2020
Background: A new virus broke out in Wuhan, Hubei, China, and was later named 2019 novel coronavirus (2019-nCoV). The clinical characteristics of severe pneumonia caused by 2019-nCoV are still not clear.
Yafei Wang, Ying Zhou, Zhen Yang, Dongping Xia, S. Geng   +4 more
semanticscholar   +1 more source

Diagnosis and management of pneumonia in the emergency department. [PDF]

, 2008
Pneumonia is a condition that is often treated by emergency physicians. This article reviews the diagnosis and management of pneumonia in the emergency department and highlights dilemmas in diagnostic testing, use of blood and sputum cultures, hospital ...
Abrahamian, Fredrick M, Moran, Gregory J, Talan, David A   +2 more
core  

Point-of-care measurement of blood lactate in children admitted with febrile illness to an African District Hospital. [PDF]

, 2011
BACKGROUND: Lactic acidosis is a consistent predictor of mortality owing to severe infectious disease, but its detection in low-income settings is limited to the clinical sign of "deep breathing" because of the lack of accessible technology for its ...
Acierno, B. Amos, B. Nadjm, Day, English, English, English, F. Muro, G. Mtove, Gore, H. Reyburn, I. C. E. Hendriksen, J. Todd, Kahigwa, Krishna, Krishna, Maitland, Marsh, Marsh, Molyneux, Nadjm, Reyburn, Taylor   +22 more
core   +1 more source

Incidence and Risk Factors for Severe Pneumonia in Children Hospitalized with Pneumonia in Ujjain, India

International Journal of Environmental Research and Public Health, 2020
Childhood pneumonia is a major public health problem. The aim of this prospective hospital-based study is to determine the incidence and risk factors for community-acquired severe pneumonia in children in Ujjain, India.
S. Kasundriya, Mamta Dhaneria, Aditya Mathur, A. Pathak   +3 more
semanticscholar   +1 more source

Clinical and in vitro efficacy of colistin plus vancomycin and rifampin against colistin-resistant Acinetobacter baumannii causing ventilator-associated pneumonia [PDF]

, 2017
We present the case of a patient with ventilator-associated pneumonia (VAP) caused by a pan-resistant Acinetobacter baumannii successfully treated with the combination colistin plus vancomycin plus rifampin, whose in vitro activity was investigated by ...
Cipolla, Alessia, Falcone, Marco, Mastroianni, Claudio Maria, Oliva, Alessandra, Venditti, Mario, Vullo, Vincenzo   +5 more
core   +1 more source

Identifying which septic patients have increased mortality risk using severity scores:a cohort study [PDF]

, 2014
Background: Early aggressive therapy can reduce the mortality associated with severe sepsis but this relies on prompt recognition, which is hindered by variation among published severity criteria. Our aim was to test the performance of different severity
Davey, Peter G, Evans, Josie Mm, Guthrie, Bruce, Marwick, Charis A, McLeod, Shaun R, Pringle, Jan Ec   +5 more
core   +4 more sources

Clinical Characteristics of Patients with Severe Pneumonia Caused by the SARS-CoV-2 in Wuhan, China

Respiration, 2020
Background: A new virus broke out in Wuhan, Hubei, China, that was later named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The clinical characteristics of severe pneumonia caused by SARS-CoV-2 are still not clear. Objectives: The aim of
Yafei Wang, Ying Zhou, Zhen Yang, Dongping Xia, Y. Hu, S. Geng   +5 more
semanticscholar   +1 more source

Research progress of biomarkers in evaluating the severity and prognostic value of severe pneumonia in children

Frontiers in Pediatrics
Pneumonia is a serious and common infectious disease in children. If not treated in time, it may develop into severe pneumonia. Severe pneumonia in children is mainly characterized by hypoxia and acidosis, often accompanied by various complications such ...
Weihua Gong, Kaijie Gao, Zhiming Shan, Liu Yang, Panpan Fang, Ci Li, Junmei Yang, Jiajia Ni   +7 more
doaj   +1 more source