Results 51 to 60 of about 12,213 (202)

The Expansion of Myeloid-Derived Suppressor Cells Correlates With the Severity of Pneumonia in Kidney Transplant Patients

Frontiers in Medicine, 2022
BackgroundPneumonia is one of the most frequent but serious infectious complications post kidney transplantation. Severe pneumonia induces sustained immunosuppression, but few parameters concerning immune status are used to assess the severity of ...
Bo Peng, Bo Peng, Yulin Luo, Yulin Luo, Quan Zhuang, Quan Zhuang, Junhui Li, Junhui Li, Pengpeng Zhang, Pengpeng Zhang, Min Yang, Min Yang, Yu Zhang, Yu Zhang, Gangcheng Kong, Gangcheng Kong, Ke Cheng, Ke Cheng, Yingzi Ming, Yingzi Ming   +19 more
doaj   +1 more source

Beyond Visual Scoring: Computational CT‐analysis for HRCT based quantification of Interstitial Lung Disease in Inflammatory Rheumatic Disease

Arthritis Care &Research, Accepted Article.
Interstitial lung disease (IRD‐ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRD). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the non‐invasive assessment of ILD; however, its interpretation is constrained by substantial inter‐observer variability and ...
Alexander Pfeil, Tobias Hoffmann, Ulf Teichgräber, Diane Renz, Denise Beckmann, Gunter Wolf, Nicole Schadewaldt, Bianca Lassen‐Schmidt   +7 more
wiley   +1 more source

Severe Community-Acquired Pneumonia [PDF]

Anaesthesia and Intensive Care, 1997
Severe community-acquired pneumonia is now considered a separate clinical entity that is important to recognize, particularly because of its high mortality rate. This article reviews several of the studies published in the past year that focus on risk and prognostic factors, etiology, diagnostic evaluation, pathogenesis, and therapy of this important ...
openaire   +4 more sources

Assessment of Antibiotic Use in ICU Patients with Pneumonia Using ATC/DDD as a Quantitative Analysis Method

Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2022
Background: Pneumonia is an infection of the lung tissue which is mainly caused by bacteria. High utilization and inappropriate use of antibiotics increase resistant bacteria, morbidity, mortality, and treatment cost.
Mareta Rindang Andarsari, Zedny Norachuriya, Sarah Mahmudatun Nabila, Toetik Aryani, Alfian Nur Rosyid   +4 more
doaj   +1 more source

Dynamically Actuated Reconfigurable Topographical Surface Enables Active Control of Implant‐Associated Infections

Advanced Functional Materials, EarlyView.
A dynamically actuated reconfigurable topographical surface (DARTS) integrates contact‐mediated bactericidal nanotopography with programmable mechanical actuation to actively disrupt bacterial biofilms. Dynamic surface reconfiguration enhances bacterial killing and suppresses implant‐associated infections in vivo, providing a new strategy for active ...
Mohammad Asadi Tokmedash, Jihun Lee, J. Scott VanEpps, Sungmin Nam, Jouha Min   +4 more
wiley   +1 more source

Thrombosis biomarkers: utility in early diagnosis and prognosis of severe pneumonia

Thrombosis Journal
Background Pneumonia is a major health problem and the most important causes of mortality in all age groups worldwide. We investigated new automation technology to detect plasma biomarkers, including thrombinantithrombin complex (TAT), α2 ...
Yanru Fan, Rufei Ma, Yuan Zhang, Biao Hu, Huiling Wang, Lan Gao   +5 more
doaj   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Predictive value of combined serum IL-6 with UREA on severity of neonatal pneumonia: an observational study

Journal of Laboratory Medicine, 2023
IL-6 is an inflammatory marker and urea nitrogen (UREA) is a common indicator of glomerular filtration function. Their combined detection has predictive value for the severity of neonatal pneumonia.
Li Ci, Xu Zhe, Sun Hongqi, Yang Liu, Nie Manjie, Gong Weihua, Yang Junmei, Li Tiewei   +7 more
doaj   +1 more source

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source