Results 21 to 30 of about 3,781,222 (303)

An Adjudication Protocol for Severe Pneumonia

Open Forum Infectious Diseases, 2023
Background Clinical end points that constitute successful treatment in severe pneumonia are difficult to ascertain and vulnerable to bias. The utility of a protocolized adjudication procedure to determine meaningful end points in severe pneumonia has not
Chiagozie I. Pickens, C. Gao, J. Bodner, J. Walter, J. Kruser, H. Donnelly, A. Donayre, K. Clepp, N. Borkowski, R. Wunderink, Benjamin D. Singer   +10 more
semanticscholar   +1 more source

SEVERE PNEUMONIA;

The Professional Medical Journal, 2018
Background: The signs and symptoms of pneumonia are often nonspecificand widely vary based on the patient’s age and the infectious organisms involved. IMNCI hasimproved case improved diagnose of pneumonia. This study was conducted to study thefrequency of correctly diagnosed cases of severe pneumonia by IMNCI classification in childrenbetween 2 – 59 ...
Asim Amjad, Ubaid ullah, Iqbal Ahmad Azhar   +2 more
openaire   +3 more sources

Metabolic biomarker profiling for identification of susceptibility to severe pneumonia and COVID-19 in the general population

eLife, 2021
Biomarkers of low-grade inflammation have been associated with susceptibility to a severe infectious disease course, even when measured prior to disease onset.
H. Julkunen, A. Cichońska, P. Slagboom, P. Würtz   +3 more
semanticscholar   +1 more source

A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia

New England Journal of Medicine, 2020
Background Convalescent plasma is frequently administered to patients with Covid-19 and has been reported, largely on the basis of observational data, to improve clinical outcomes. Minimal data are available from adequately powered randomized, controlled
V. Simonovich, Leandro D Burgos Pratx, P. Scibona, M. V. Beruto, M. Vallone, C. Vázquez, Nadia Savoy, D. Giunta, Lucia Perez, M. Sanchez, A. Gamarnik, D. Ojeda, Diego M Santoro, P. J. Camino, Sebastian Antelo, Karina Rainero, G. Vidiella, E. Miyazaki, W. Cornistein, Omar Trabadelo, F. Ross, M. Spotti, Gabriel Funtowicz, W. Scordo, M. Losso, I. Ferniot, Pablo E Pardo, Eulalia Rodríguez, P. Rucci, J. Pasquali, N. Fuentes, M. Esperatti, G. Speroni, E. Nannini, Alejandra Matteaccio, H. Michelangelo, D. Follmann, H. Lane, W. Belloso   +38 more
semanticscholar   +1 more source

Viral reactivation in the lungs of patients with severe pneumonia is associated with increased mortality, a multicenter, retrospective study

Journal of Medical Virology, 2022
Viral reactivation is widespread in patients with severe pneumonia, yet the landscape of viral reactivation in the lungs is not well‐known. This study aims to assess the landscape and clinical features of viral reactivation in the early onset of severe ...
Ling-na Huang, Xuan-Xuan Zhang, Lisha Pang, P. Sheng, Yanqiu Wang, Fan Yang, Huili Yu, Xiaohan Huang, Yue Zhu, Ning Zhang, H. Cai, Lingling Tang, Xue-ling Fang   +12 more
semanticscholar   +1 more source

Bacterial coinfection in critically ill COVID-19 patients with severe pneumonia

Infection, 2021
Severe 2019 novel coronavirus infectious disease (COVID-19) with pneumonia is associated with high rates of admission to the intensive care unit (ICU). Bacterial coinfection has been reported to be rare.
Alexandre Elabbadi, M. Turpin, G. Gerotziafas, Marion Teulier, G. Voiriot, M. Fartoukh   +5 more
semanticscholar   +1 more source

Clinical Symptoms and Outcomes of Severe Pneumonia Caused by Chlamydia psittaci in Southwest China

Frontiers in Cellular and Infection Microbiology, 2022
Here, we aimed to retrospectively analyze the clinical characteristics of 27 patients with severe pneumonia caused by Chlamydia psittaci between January 2019 and April 2021 in southwest China.
Fuxun Yang, Jiajia Li, Boyang Qi, L. Zou, Zongming Shi, Yu Lei, Jun Yu Li, Xiaoxiu Luo, Fan Zeng, Sen Lu, Xiaobo Huang, Rongan Liu, Yunping Lan   +12 more
semanticscholar   +1 more source

A case of chlamydia psittaci caused severe pneumonia and meningitis diagnosed by metagenome next-generation sequencing and clinical analysis: a case report and literature review

BMC Infectious Diseases, 2021
Background Psittacosis, which is also known as parrot fever, is Chlamydia psittaci (C. psittaci) caused infectious disease . The clinical manifestations vary from asymptomatic infection to severe atypical pneumonia or even fatal meningitis.
Yunfeng Shi, Junxian Chen, Xiaohan Shi, Jiajia Hu, Hongtao Li, Xiao-jing Li, Yan-Hong Wang, Benquan Wu   +7 more
semanticscholar   +1 more source

Effect of Vitamin C on mortality of critically ill patients with severe pneumonia in intensive care unit: a preliminary study

BMC Infectious Diseases, 2021
Background Critically ill patients frequently suffer from vitamin C deficiency. Previous studies showed that high doses of vitamin C administration had conflicting results on clinical outcomes in patients with severe sepsis, burns, and trauma. Because of
A. Mahmoodpoor, Kamran Shadvar, S. Sanaie, Mir Reza Hadipoor, Mohammad Ata Pourmoghaddam, S. Saghaleini   +5 more
semanticscholar   +1 more source

Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia

Journal of Thrombosis and Haemostasis, 2020
In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.
N. Tang, Dengju Li, Xiong Wang, Ziyong Sun   +3 more
semanticscholar   +1 more source