Results 51 to 60 of about 410,515 (250)

Recommendations for diagnosing and treating severe Mycoplasma pneumoniae pneumonia in children: clinical practice protocols from the Third Affiliated Hospital of Sun Yat-sen University [PDF]

Xin yixue
Mycoplasma pneumoniae pneumonia （MPP） is a common cause of community-acquired pneumonia in children aged 5 and older in China. Although most affected children have favorable clinical prognosis， some cases can escalate into severe MPP due to risk factors ...
YANG Kexin, PAN Li, ZENG Jinqing, LI Zhongke, LI Xufeng, ZHU Lingping, LIANG Ying, YANG Lifen, ZHANG Kun, DAI Min, CHEN Zhuanggui, LI Yating
doaj   +1 more source

Influenza A-associated severe pneumonia in hospitalized patients: Risk factors and NAI treatments

International Journal of Infectious Diseases, 2020
Objective: The risk factors and the impact of NAI treatments in patients with severe influenza A-associated pneumonia remain unclear. Methods: A multicenter, retrospective, observational study was conducted in Zhejiang, China during a severe influenza ...
Qianda Zou, Shufa Zheng, Xiaochen Wang, Sijia Liu, Jiaqi Bao, Fei Yu, Wei Wu, Xianjun Wang, Bo Shen, Tieli Zhou, Zhigang Zhao, Yiping Wang, Ruchang Chen, Wei Wang, Jianbo Ma, Yongcheng Li, Xiaoyan Wu, Weifeng Shen, Fuyi Xie, Dhanasekaran Vijaykrishna, Yu Chen   +20 more
doaj   +1 more source

The Expansion of Myeloid-Derived Suppressor Cells Correlates With the Severity of Pneumonia in Kidney Transplant Patients

Frontiers in Medicine, 2022
BackgroundPneumonia is one of the most frequent but serious infectious complications post kidney transplantation. Severe pneumonia induces sustained immunosuppression, but few parameters concerning immune status are used to assess the severity of ...
Bo Peng, Bo Peng, Yulin Luo, Yulin Luo, Quan Zhuang, Quan Zhuang, Junhui Li, Junhui Li, Pengpeng Zhang, Pengpeng Zhang, Min Yang, Min Yang, Yu Zhang, Yu Zhang, Gangcheng Kong, Gangcheng Kong, Ke Cheng, Ke Cheng, Yingzi Ming, Yingzi Ming   +19 more
doaj   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Assessment of Antibiotic Use in ICU Patients with Pneumonia Using ATC/DDD as a Quantitative Analysis Method

Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2022
Background: Pneumonia is an infection of the lung tissue which is mainly caused by bacteria. High utilization and inappropriate use of antibiotics increase resistant bacteria, morbidity, mortality, and treatment cost.
Mareta Rindang Andarsari, Zedny Norachuriya, Sarah Mahmudatun Nabila, Toetik Aryani, Alfian Nur Rosyid   +4 more
doaj   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Severe Community-Acquired Pneumonia [PDF]

Anaesthesia and Intensive Care, 1997
Severe community-acquired pneumonia is now considered a separate clinical entity that is important to recognize, particularly because of its high mortality rate. This article reviews several of the studies published in the past year that focus on risk and prognostic factors, etiology, diagnostic evaluation, pathogenesis, and therapy of this important ...
openaire   +4 more sources

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source