Results 171 to 180 of about 46,272 (261)

Nonclinical Considerations for Support of Pregnancy and Lactation in Clinical Trials

Birth Defects Research, Volume 118, Issue 6, June 2026.
ABSTRACT Background Pregnant and breastfeeding individuals remain underrepresented in clinical drug development, leaving health care providers and patients with limited data to inform treatment decisions. Current practice relies heavily on nonclinical developmental and reproductive toxicity (DART) studies in animals, while clinical trials typically ...
Dinesh Stanislaus, Christopher J. Bowman, Kimberly C. Brannen, Sarah N. Campion, Laura M. Carlson, Stephan Chalon, Anthony M. DeLise, Claudia Demarta‐Gatsi, Brian P. Enright, Wendy Halpern, Shermaine Mitchell‐Ryan, Vicki Sutherland, Karen Thacker, Kary Thompson, Belen Tornesi, Steven Van Cruchten, Ronald L. Wange, Tacey White, Connie L. Chen   +18 more
wiley   +1 more source

Serum heat shock protein 90 alpha levels in mild and severe preeclampsia. [PDF]

Rev Assoc Med Bras (1992)
Canbolat KH, Açıkgöz AS, Gök K, Tüten A, Kaya B, Gayretli TK, Özçil MD, Malik E, Güralp O.   +8 more
europepmc   +1 more source

Hydranencephaly in Neonate With Prenatal Exposure to Alcohol During Pregnancy

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Hydranencephaly (HE) is a rare congenital condition characterized by near‐total absence of the cerebral hemispheres, replaced by cerebrospinal fluid, most commonly resulting from in utero bilateral internal carotid artery occlusion; although maternal alcohol consumption is associated with fetal neurodevelopmental abnormalities, its direct role
Dibya Raj Chaudhary, Diwakar Koirala, Samiksha Lamichhane, Bivek Mishra   +3 more
wiley   +1 more source

Noninvasive Maternal-Fetal Hemodynamic Monitoring as A Predictor of Severe Preeclampsia in Low-Resource Settings: A Case Report. [PDF]

AJP Rep
Toledo-Jaldin L, Gomez R, Lazo-Vega L, Larrea A, Vásquez A, Ormachea-Orellana W, Miranda-Girrado V, Julian CG.   +7 more
europepmc   +1 more source

Noninvasive blood pressure measurements demonstrated a significant underestimation of blood pressure in a patient with severe preeclampsia: a case report. [PDF]

Int J Surg Case Rep
Zhang Y, Gu J, Yu C.
europepmc   +1 more source

Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
This review summarizes how maternal health and nutrition shape gut microbiota via epigenetics to regulate embryonic development. It highlights microbiota‐embryo interactions, disruption by prenatal chemical exposures, and personalized nutrition for disease prevention, offering novel insights and therapeutic targets.
Shoulong Xu, Yanjiao Huang, Chenyue Hu, Wenli Ding, Zhenwei Pu, Qiang Li, Zhiliang Xu   +6 more
wiley   +1 more source

Intracerebral Hemorrhage: A Fatal Complication of Severe Preeclampsia-A Rare Case Report in a Resource-Limited Setting. [PDF]

Int Med Case Rep J
Mohamed IA, Omar AA, Hassan MM, Hassan MA, Adan ZM, Mohamed ZA.   +5 more
europepmc   +1 more source

Maternal Cardiac Arrest in Severe Preeclampsia at 34 Weeks: Successful Resuscitation, Perimortem Cesarean Section, and Dual Survival. [PDF]

Cureus
Deori P, Karim HMR, Sharma SJ, Malakar H, Chowdhury SK, Kumari S, Hazarika D, Lal NM, Sasidharan R.   +8 more
europepmc   +1 more source

Predictors of adverse pregnancy outcomes in severe preeclampsia: A retrospective observational study. [PDF]

Medicine (Baltimore)
Li P, Jiang Y, You Y.
europepmc   +1 more source

Maternal and Neonatal Outcomes of Immune Thrombocytopenia in Pregnancy: A Five‐Year Single‐Center Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Objectives Immune thrombocytopenia (ITP) during pregnancy presents unique management challenges. This study represents the first analysis of ITP outcomes during pregnancy in Qatar, aiming to assess maternal and neonatal outcomes at a tertiary care center.
Sara Elkorashi, Hassan Magboul, Abdulrahman F. Al‐Mashdali, Mohammed Alnajjar, Naela AlMallahi, Elmustafa Abdalla, Dina Sameh Soliman, Sara Aldali, Manar Elsheikh, Honar Cherif, Shehab F. Mohamed   +10 more
wiley   +1 more source